{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T20:20:17Z","timestamp":1772223617600,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T00:00:00Z","timestamp":1513036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Photoaggravated allergic contact dermatitis caused by methylchloroisothiazolinone (MCI)\/methylisothiazolinone (MI) and MI has been reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe the clinical characteristics and results of (photo)patch tests and photo\u2010tests of 10 patients in Belgium and France suffering from photoaggravated contact dermatitis caused by MI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>Five men and five women, with a median age of 49.5\u2009years, were investigated between January 2012 and February 2017 because of suspected photoaggravated contact dermatitis. Patch tests, photopatch tests and\/or photo\u2010tests were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven patients had positive patch test reactions to both MCI\/MI and MI, whereas 3 patients had positive patch test reactions only to MI. In most cases, MI was the (strong) primary sensitizer. Photopatch tests with MCI\/MI and\/or MI gave stronger reactions than patch tests with these derivatives, indicating photoaggravation. Sensitization probably took place from cosmetics and work\u2010related biocides, whereas elicitation of dermatitis was remarkably often related to airborne exposure to MI present in paints or industrial biocides. Four patients suffered from transient photosensitivity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Photoaggravated allergic contact dermatitis and transient photosensitivity caused by MI is a peculiar clinical presentation of allergic contact dermatitis caused by this preservative, and should be considered in daily clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12926","type":"journal-article","created":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T08:18:55Z","timestamp":1513066735000},"page":"241-245","source":"Crossref","is-referenced-by-count":30,"title":["Photoaggravated allergic contact dermatitis and transient photosensitivity caused by methylisothiazolinone"],"prefix":"10.1111","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0076-2887","authenticated-orcid":false,"given":"Olivier","family":"Aerts","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospital Antwerp (UZA) and University of Antwerp (UA)  2650 Antwerp Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9805-3439","authenticated-orcid":false,"given":"An","family":"Goossens","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospitals KU Leuven  3000 Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie\u2010Claude","family":"Marguery","sequence":"additional","affiliation":[{"name":"Service Dermatologie H\u00f4pital Larrey, CHU Toulouse  31059 Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Castelain","sequence":"additional","affiliation":[{"name":"Dermatologie Avenue de Montredon  13008 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucile","family":"Boursault","sequence":"additional","affiliation":[{"name":"Service Dermatologie H\u00f4pital St Andr\u00e9, CHU Bordeaux  33000 Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7oise","family":"Giordano\u2010Labadie","sequence":"additional","affiliation":[{"name":"Service Dermatologie H\u00f4pital Larrey, CHU Toulouse  31059 Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien","family":"Lambert","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Antwerp (UZA) and University of Antwerp (UA)  2650 Antwerp Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3679-6613","authenticated-orcid":false,"given":"Brigitte","family":"Milpied","sequence":"additional","affiliation":[{"name":"Service Dermatologie H\u00f4pital St Andr\u00e9, CHU Bordeaux  33000 Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12249"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13986"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12432"},{"key":"e_1_2_5_5_1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1684\/ejd.2016.2951","article-title":"Contact allergy caused by isothiazolinone\u2010derivatives: an overview of non\u2010cosmetic and unusual cosmetic sources","volume":"27","author":"Aerts O","year":"2017","journal-title":"Eur J Dermatol"},{"key":"e_1_2_5_6_1","unstructured":"GouveiaA I LopesL CorreiaT Soares\u2010de\u2010AlmeidaL. Dermite de contacto al\u00e9rgica \u00e0 metilisotiazolinona fotoagravada.Proceedings of the 15th National Congress of Dermatology and Venereology Oporto Portugal 6\u20138 November 2015."},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-014-3557-x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12718"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2016.06.001"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1091581810374651"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12733"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcod.12926","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.12926","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T18:00:38Z","timestamp":1695492038000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.12926"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,12]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1111\/cod.12926"],"URL":"https:\/\/doi.org\/10.1111\/cod.12926","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,12]]}}}