{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T12:39:13Z","timestamp":1760013553455,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,11,27]],"date-time":"2017-11-27T00:00:00Z","timestamp":1511740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The use of metal\u2010containing bio\u2010devices is becoming increasingly common. Self\u2010reported history of dermatitis with metal exposure is not established as being predictive for metal allergy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the validity of two screening questions addressing metal allergy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>At Massachusetts General Hospital Contact Dermatitis Clinic, 2132 consecutive patients were asked either \u2018Do you get rashes when jewellery touches your skin\u2019 (Q1; N\u2009=\u20091816) or \u2018Do you get rashes when metal touches your skin?\u2019 (Q2; N\u2009=\u2009316) before being patch tested.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Testing showed that 20% of subjects had positive reactions to nickel, 7.4% had positive reactions to cobalt, and 5.8% had positive reactions to chromium. Q1 was 40% sensitive (95%CI: 35\u201345%). The positive predictive value (PPV) was 51%, and the negative predictive value (NPV) was 82%. Q2 was 77% sensitive (95%CI: 68\u201384%). The PPV was 71%, and the NPV was 84%. Q2 was 37% more sensitive than Q1 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), with a higher relative risk (RR) (4.75, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) than Q1 (RR\u2009=\u20093.01, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patient\u2010reported metal allergy, although not perfect, is a reasonable method for metal allergy screening to help identify those needing further objective evaluation by patch testing.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.12928","type":"journal-article","created":{"date-parts":[[2017,11,27]],"date-time":"2017-11-27T07:46:46Z","timestamp":1511768806000},"page":"208-210","source":"Crossref","is-referenced-by-count":10,"title":["Assessing the validity of self\u2010reported history of rash caused by metal or jewellery"],"prefix":"10.1111","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6281-2421","authenticated-orcid":false,"given":"Lauren N.","family":"Ko","sequence":"first","affiliation":[{"name":"Harvard Medical School  Boston MA 02115 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Kroshinsky","sequence":"additional","affiliation":[{"name":"Department of Dermatology Massachusetts General Hospital  Boston MA 02114 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter C.","family":"Schalock","sequence":"additional","affiliation":[{"name":"Department of Dermatology Massachusetts General Hospital  Boston MA 02114 USA"},{"name":"Department of Surgery (Dermatology) Geisel School of Medicine at Dartmouth  Hanover NH 03755 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,27]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_5_2_1","DOI":"10.1007\/s40629-014-0013-5"},{"doi-asserted-by":"publisher","key":"e_1_2_5_3_1","DOI":"10.2310\/6620.2009.08097"},{"doi-asserted-by":"publisher","key":"e_1_2_5_4_1","DOI":"10.1007\/s00018-011-0846-8"},{"key":"e_1_2_5_5_1","first-page":"233","volume-title":"Dermatology","author":"Mowad C M","year":"2012"},{"doi-asserted-by":"publisher","key":"e_1_2_5_6_1","DOI":"10.1111\/j.1600-0536.2007.01257.x"},{"doi-asserted-by":"publisher","key":"e_1_2_5_7_1","DOI":"10.1053\/ajcd.2000.8587"},{"doi-asserted-by":"publisher","key":"e_1_2_5_8_1","DOI":"10.1111\/j.1600-0536.1979.tb04913.x"},{"doi-asserted-by":"publisher","key":"e_1_2_5_9_1","DOI":"10.1055\/s-0034-1381959"},{"doi-asserted-by":"publisher","key":"e_1_2_5_10_1","DOI":"10.1111\/j.1600-0536.2010.01702.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s11886-014-0489-0","article-title":"Approval of high\u2010risk medical devices in the US: implications for clinical cardiology","volume":"16","author":"Rome B N","year":"2014","journal-title":"Curr Cardiol Rep"},{"doi-asserted-by":"publisher","key":"e_1_2_5_12_1","DOI":"10.1111\/j.1600-0536.1987.tb02718.x"},{"doi-asserted-by":"publisher","key":"e_1_2_5_13_1","DOI":"10.1111\/cod.12583"},{"doi-asserted-by":"publisher","key":"e_1_2_5_14_1","DOI":"10.1111\/j.1600-0536.2009.01572.x"},{"doi-asserted-by":"publisher","key":"e_1_2_5_15_1","DOI":"10.1111\/j.1610-0387.2011.07671_suppl.x"},{"doi-asserted-by":"publisher","key":"e_1_2_5_16_1","DOI":"10.1097\/DER.0000000000000210"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcod.12928","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.12928","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T13:29:46Z","timestamp":1695734986000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.12928"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,27]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1111\/cod.12928"],"URL":"https:\/\/doi.org\/10.1111\/cod.12928","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"type":"print","value":"0105-1873"},{"type":"electronic","value":"1600-0536"}],"subject":[],"published":{"date-parts":[[2017,11,27]]}}}