{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:21:29Z","timestamp":1790396489655,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T00:00:00Z","timestamp":1526515200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004954","name":"Augustinus Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004954","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Sickness absence in hand eczema patients has been associated with stress rather than disease severity, indicating that personal aspects regarding hand eczema should be investigated further.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To examine whether patient education vs treatment as usual can influence behaviour and knowledge regarding skin protection and care, as well as personal resources, in patients with occupational hand eczema.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>PREVEX is an individually randomized clinical trial investigating the 1\u2010year effects of a simple, low\u2010cost group\u2010counselling programme vs treatment as usual for patients with notified occupational hand eczema. Exploratory outcomes were behaviour, knowledge, self\u2010efficacy, and self\u2010evaluated skin care ability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 1668 patients with notified occupational skin disease were invited to participate, of whom 769 were randomized and 756 were analysed: intervention group (<jats:italic>n<\/jats:italic>\u2009=\u2009376) vs control group (<jats:italic>n<\/jats:italic>\u2009=\u2009380). Behaviour was improved and the knowledge score increased in the intervention group as compared with the control group (respectively: estimate 0.08; 95%CI: 0.02\u20100.19; <jats:italic>P<\/jats:italic>\u2009=\u2009.01; and estimate 0.49; 95%CI: 0.28\u20100.70; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). Self\u2010efficacy was lower in the intervention group as compared with the control group (estimate \u22120.78; 95%CI: \u22121.25 to \u22120.30; <jats:italic>P<\/jats:italic>\u2009=\u2009.001). No difference was found regarding skin care abilities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The intervention had a positive influence on 1\u2010year behaviour and knowledge, but was insufficient to result in long\u2010term positive changes in personal resources regarding dealing with hand eczema.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13003","type":"journal-article","created":{"date-parts":[[2018,5,18]],"date-time":"2018-05-18T01:36:14Z","timestamp":1526607374000},"page":"127-135","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Simple, low\u2010cost group\u2010counselling programme vs treatment as usual for patients with newly notified occupational hand eczema\u2014Exploratory analyses of effects on knowledge, behaviour and personal resources of the randomized PREVEX clinical trial"],"prefix":"10.1111","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8800-9613","authenticated-orcid":false,"given":"Maja H.","family":"Fisker","sequence":"first","affiliation":[{"name":"Department of Occupational and Environmental Medicine Bispebjerg Hospital, University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tove","family":"Agner","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bispebjerg Hospital, University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine Bispebjerg Hospital, University of Copenhagen  Copenhagen Denmark"},{"name":"Department of Dermatology Bispebjerg Hospital, University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren G.","family":"Vejlstrup","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine Bispebjerg Hospital, University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Lindschou","sequence":"additional","affiliation":[{"name":"Copenhagen Trial Unit (CTU) Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Gluud","sequence":"additional","affiliation":[{"name":"Copenhagen Trial Unit (CTU) Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Winkel","sequence":"additional","affiliation":[{"name":"Copenhagen Trial Unit (CTU) Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens P.","family":"Bonde","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine Bispebjerg Hospital, University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels E.","family":"Ebbeh\u00f8j","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine Bispebjerg Hospital, University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,17]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2009.01669.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01305.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1990.tb00076.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06494.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e7822"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.02024.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12243"},{"key":"e_1_2_8_9_1","unstructured":"Labour Market Insurance (Arbejdsmarkedets Erhvervssikring) TABLE. 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