{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T12:37:32Z","timestamp":1778243852402,"version":"3.51.4"},"reference-count":60,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,9,4]],"date-time":"2018-09-04T00:00:00Z","timestamp":1536019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Colophonium is a natural substance derived from Pineaceae trees. It is used in a wide range of consumer and occupational products because of its tackiness, and is a known sensitizer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To analyse the temporal trend of contact allergy to colophonium in north\u2010eastern Italy, and to evaluate the associations with occupations in our geographical area.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>From 1996 to 2016, 27 381 patients with suspected allergic contact dermatitis were patch tested in north\u2010eastern Italy. Individual characteristics were documented by use of a standardized questionnaire in 6 departments of dermatology or occupational medicine.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall prevalence of colophonium sensitization was 1.67%; the prevalence was significantly higher in women (1.75%) than in men (1.49%). No significant differences among departments were observed. We found significant associations between colophonium sensitization and being a student (odds ratio [OR] 4.64; 95% confidence interval [CI]: 1.04\u201020.6), being a farmer or fishermen (OR 3.63; 95%CI: 1.21\u201010.84), being a housekeeper (OR 2.02; 95%CI: 1.08\u20103.77), and being retired (OR 2.06; 95%CI: 1.08\u20103.92).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study showed that contact allergy to colophonium is still relevant in north\u2010eastern Italy. The frequency of sensitization has dropped significantly over a period of 10 years, but students and farmers\/fishermen still have sensitization prevalences above 3.5%. Our results are in line with European data.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13089","type":"journal-article","created":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T06:26:06Z","timestamp":1536128766000},"page":"303-309","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Sensitization to, and allergic contact dermatitis caused by, colophonium in north\u2010eastern Italy in 1996 to 2016 with a focus on occupational exposures"],"prefix":"10.1111","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1317-3448","authenticated-orcid":false,"given":"Marcella","family":"Mauro","sequence":"first","affiliation":[{"name":"Department of Medical Sciences, Clinical Unit of Occupational Medicine University of Trieste  Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Belloni","family":"Fortina","sequence":"additional","affiliation":[{"name":"Padua Hospital Internal Medicine Department \u2010 DIMED, Paediatric Dermatology Unit University of Padua  Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Corradin","sequence":"additional","affiliation":[{"name":"Pordenone Hospital \u2010 Internal and Specialistic Department Ospedale Santa Maria degli Angeli  Pordenone Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Marino","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Clinical Unit of Occupational Medicine University of Trieste  Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Bovenzi","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Clinical Unit of Occupational Medicine University of Trieste  Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7717-0417","authenticated-orcid":false,"given":"Francesca Larese","family":"Filon","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Clinical Unit of Occupational Medicine University of Trieste  Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,4]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1","article-title":"Contact allergy to colophony. 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