{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T11:05:23Z","timestamp":1782126323562,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,11,13]],"date-time":"2018-11-13T00:00:00Z","timestamp":1542067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>There was a global epidemic of methylchloroisothiazolinone (MCI) and\/or methylisothiazolinone (MI) contact allergy from 2009 to 2015. In response, the Thai Ministry of Public Health regulated the use of MCI\/MI in cosmetics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To survey the presence of MCI\/MI and MI alone, as labelled on cosmetics sold on the Thai market, before and after the ministerial directive.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The presence of MCI and\/or MI in leave\u2010on and rinse\u2010off cosmetics sold on the market, based on the labelling of ingredients in 3445 products, was analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Before the implementation date, most leave\u2010on products contained MCI\/MI. After the regulations came into force, the only leave\u2010on cosmetic subcategories that complied with the law were facial skin\u2010care, sunscreen and make\u2010up products. MCI\/MI and MI alone were found on the labels of both leave\u2010on and rinse\u2010off products, the presence of each varying between product subcategories.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Despite the ministerial regulations restricting their use, MCI and\/or MI are still found in cosmetics sold on the Thai market. Dermatologists should be aware of this situation, and counsel patients to avoid products containing MCI and\/or MI.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13151","type":"journal-article","created":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T07:00:20Z","timestamp":1542178820000},"page":"110-113","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Methylchloroisothiazolinone and\/or methylisothiazolinone in cosmetic products\u2014A market survey"],"prefix":"10.1111","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5351-2988","authenticated-orcid":false,"given":"Thanisorn","family":"Sukakul","sequence":"first","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dollaporn","family":"Kanchanapenkul","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monthathip","family":"Bunyavaree","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pichaya","family":"Limphoka","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Titinun","family":"Kumpangsin","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6673-6534","authenticated-orcid":false,"given":"Waranya","family":"Boonchai","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e31827edc73"},{"key":"e_1_2_6_3_1","first-page":"467071","article-title":"Contact\u2010allergic reactions to cosmetics","author":"Goossens A","year":"2011","journal-title":"J Allergy (Cairo)"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12733"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000105"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000061"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000031"},{"key":"e_1_2_6_8_1","unstructured":"Commission Regulation (EU) No 1003\/2014 of 18 September 2014 amending Annex V to Regulation (EC) No 1223\/2009 of the European Parliament and of the Council on cosmetic products Text with EEA relevance. OJ L 282 26.9.2014; 1\u20134."},{"key":"e_1_2_6_9_1","unstructured":"AEC and Challenges of Thai Cosmetics Industry edn: Bangkok Thailand Information Centre 2012.http:\/\/tic.car.chula.ac.th\/th\/component\/flexicontent\/95\u2010aec2\/36628\u2010aec\u2010and\u2010challenges\u2010of\u2010thai\u2010cosmetics\u2010industry. Accessed November 6 2018."},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2010.01828.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12676"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12595"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000288"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1203475417690307"},{"key":"e_1_2_6_15_1","unstructured":"Regulation (EC) No 1223\/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products (Text with EEA relevance). OJ L 342 22.12.2009; 59\u2013209."},{"key":"e_1_2_6_16_1","unstructured":"European Commission Scientific Committee on Consumer Safety; Opinion on Methylisothiazolinone (P94)\u2014Submission II (Sensitisation only) adopted on 12 December 2013 revision of 27 March 2014.http:\/\/ec.europa.eu\/health\/scientific_committees\/consumer_safety\/docs\/sccs_o_145.pdfAccessed September 26 2018."},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000352"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcod.13151","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.13151","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T11:11:00Z","timestamp":1694689860000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.13151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,13]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1111\/cod.13151"],"URL":"https:\/\/doi.org\/10.1111\/cod.13151","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,13]]},"assertion":[{"value":"2018-08-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}