{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T02:37:31Z","timestamp":1787884651518,"version":"build-2784847793"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T00:00:00Z","timestamp":1553817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Glucose monitoring systems, for example, Freestyle Libre (Abott) and Dexcom (Nintamed), are increasingly being used instead of conventional blood sugar measurement. However, many patients have experienced adverse skin reactions such as severe allergic contact dermatitis (ACD). Finally, in August 2017, the culprit allergen in Freestyle Libre, isobornyl acrylate (IBOA), was identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>After patients have developed ACD, it is recommended that they no longer use their glucose monitoring systems. Thus, it is important to find an alternative IBOA\u2010free device.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>Five patients presented with ACD caused by Freestyle Libre. Each was patch tested with allergens from the baseline series and from a plastics and glues series, and additionally with IBOA 0.1% pet. Gas chromatography\u2010mass spectrometry (GC\/MS) of the Freestyle Libre sensor and the Dexcom sensor was performed. The Dexcom sensor remained on the skin of all patients for at least 2\u2009days.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All patients were sensitized to IBOA. GC\/MS showed the presence of IBOA in the Freestyle Libre sensor, whereas the Dexcom sensor was IBOA\u2010free. None of the patients had skin reactions to the Dexcom sensor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with Freestyle Libre and IBOA allergy may use the Dexcom sensor as an alternative for glucose monitoring.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13248","type":"journal-article","created":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T02:29:58Z","timestamp":1550629798000},"page":"32-36","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["The Dexcom glucose monitoring system\u2014An isobornyl acrylate\u2010free alternative for diabetic patients"],"prefix":"10.1111","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8412-2667","authenticated-orcid":false,"given":"Eva","family":"Oppel","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital, LMU Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5486-1055","authenticated-orcid":false,"given":"Stefanie","family":"Kamann","sequence":"additional","affiliation":[{"name":"Department of Allergy Dermatology Feldafing  Feldafing Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz\u2010Xaver","family":"Reichl","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Periodontology University Hospital, LMU Munich  Munich Germany"},{"name":"Walther Straub Institute of Pharmacology and Toxicology Faculty of Medicine, LMU Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christof","family":"H\u00f6gg","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Periodontology University Hospital, LMU Munich  Munich Germany"},{"name":"Walther Straub Institute of Pharmacology and Toxicology Faculty of Medicine, LMU Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1932296816662949"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2018.0088"},{"key":"e_1_2_6_4_1","unstructured":"Insuliner 114: Glucosewerte einfach scannen mit Nebeneffekten.2016;3:14\u201017."},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2016.10.006"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12866"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1995.tb00554.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12503"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12873"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1932296817738076"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/1932296818762946"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12995"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13017"},{"key":"e_1_2_6_14_1","first-page":"115","article-title":"Isobornyl acrylate: an impurity in alkyl glucosides","volume":"35","author":"Foti C","year":"2016","journal-title":"Cutan Ocul 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