{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T03:19:11Z","timestamp":1792293551446,"version":"4.4.0"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T00:00:00Z","timestamp":1580860800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Allergenic fragrances are present in a wide range of products but they are not regulated in all industries to the same extent. In Europe, absorbent hygiene products (AHPs) are only covered by the general product safety directive and therefore fragrances can be used freely, whereas in cosmetics and toys the use of these ingredients is regulated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>An analytical method was developed to evaluate the presence of 24 sensitizing fragrances in AHPs. This method allows simultaneous identification and quantification and was validated using the total error approach with an acceptance value of \u00b115%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The validated method was applied to evaluate 10 scented AHPs consisting of four tampons, three panty liners, and three sanitary pads. Eight allergenic fragrances were identified in these products and five products contained at least one allergen above 10 \u03bcg\/g.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The presence of these allergens is not communicated to the consumer. This is, however, a strict requirement in other industries (eg, cosmetics, toys) to ensure adequate consumer protection. Knowing that the exposed area is more susceptible to allergens and irritants, the presence of these allergens should be disclosed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13472","type":"journal-article","created":{"date-parts":[[2020,1,17]],"date-time":"2020-01-17T13:43:50Z","timestamp":1579268630000},"page":"279-282","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Sensitizing fragrances in absorbent hygiene products"],"prefix":"10.1111","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7388-2281","authenticated-orcid":false,"given":"Bart","family":"Desmedt","sequence":"first","affiliation":[{"name":"Medicines and Health Products, Sciensano  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quinten","family":"Marcelis","sequence":"additional","affiliation":[{"name":"Medicines and Health Products, Sciensano  Brussels Belgium"},{"name":"Department of In\u2010vitro Toxicology and Dermato\u2010Cosmetology Vrije Universiteit Brussel  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dea","family":"Zhilivoda","sequence":"additional","affiliation":[{"name":"Department of In\u2010vitro Toxicology and Dermato\u2010Cosmetology Vrije Universiteit Brussel  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Deconinck","sequence":"additional","affiliation":[{"name":"Medicines and Health Products, Sciensano  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","unstructured":"MiloticD.The impact of fragrance on consumer choice.J Cons Behaviour.1996;3:179\u2010191.","DOI":"10.1002\/cb.131"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000067"},{"key":"e_1_2_6_4_1","unstructured":"EU Regulation 1223\/2009 on Cosmetic products Official Journal of the European union 342\/59 p. 1\u2013151."},{"key":"e_1_2_6_5_1","unstructured":"EU DIRECTIVE 2009\/48\/EC on the safety of toys official journal of the European union 170 P. 1\u201349."},{"key":"e_1_2_6_6_1","unstructured":"EU Directive 2001\/95\/EC on general product safety official journal of the European union 11 p 4\u201317."},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2019.05.022"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/su10114146"},{"key":"e_1_2_6_9_1","doi-asserted-by":"crossref","unstructured":"FarageMA MaibachHI.Morphology and physiological changes of genital skin and mucosa.Curr Probl Dermatol.2011;40:9\u201019.","DOI":"10.1159\/000321042"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2004.00444.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2004.00105.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.02006.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1979.04010030065027"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01040.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000136"},{"issue":"8","key":"e_1_2_6_16_1","first-page":"1173","article-title":"Contact dermatitis associated with the use of always sanitary napkins","volume":"154","author":"Eason EL","year":"1996","journal-title":"CMAJ"},{"issue":"8","key":"e_1_2_6_17_1","first-page":"8","article-title":"Always sanitary napkins: further reports and manufacturer response","volume":"155","year":"1996","journal-title":"CMAJ"},{"key":"e_1_2_6_18_1","unstructured":"Women's voices for the earth Product testing results: Always Pads 2014.http:\/\/www.womensvoices.org\/feminine-care-products\/detox-the-box\/always-pads-testing-results. 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