{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T08:27:07Z","timestamp":1771230427695,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T00:00:00Z","timestamp":1585094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Occupational skin diseases (OSDs) are the most common work\u2010related diseases in Germany and responsible for a large individual and financial burden. Therefore, a tertiary individual prevention program (TIP) is offered to patients with severe OSD who are at increased risk of abandoning their profession.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To define cost of illness (COI) of OSD in Germany and to economically evaluate the TIP from a societal perspective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this study, data on patients taking part in the TIP (September 2005 to December 2009) were collected. Sociodemographic and medical data, costs, disease severity (Osnabrueck Hand Eczema Severity Index), and quality of life (QoL; Dermatology Life Quality Index) were assessed. COI and cost\u2010effectiveness analyses were performed with a simulated control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the analysis, 1041 patients were included. Intervention costs per person were \u20ac15\u2009009 with decreasing COI over time. The incremental cost\u2010effectiveness ratio revealed expenses per patient of \u20ac8942 for a reduction in severity level and \u20ac9093 for an improvement in QoL in the base case. Considering costs for retraining, the break\u2010even point is reached if the TIP prevents retraining in approximately 64% of participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The decreased COI in this long\u2010term evaluation indicates that the TIP is cost\u2010effective in patients with severe OSD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13506","type":"journal-article","created":{"date-parts":[[2020,2,26]],"date-time":"2020-02-26T05:50:52Z","timestamp":1582696252000},"page":"361-369","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Economic evaluation of a tertiary prevention program for occupational skin diseases in Germany"],"prefix":"10.1111","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4118-1058","authenticated-orcid":false,"given":"Valerie","family":"Andrees","sequence":"first","affiliation":[{"name":"Institute for Health Services Research in Dermatology and Nursing (IVDP) University Medical Center Hamburg\u2010Eppendorf (UKE)  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Swen M.","family":"John","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Environmental Medicine and Health Theory University of Osnabr\u00fcck  Osnabr\u00fcck Germany"},{"name":"Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm), University of Osnabr\u00fcck  Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert","family":"Nienhaus","sequence":"additional","affiliation":[{"name":"Institute for Health Services Research in Dermatology and Nursing (IVDP) University Medical Center Hamburg\u2010Eppendorf (UKE)  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5670-8396","authenticated-orcid":false,"given":"Christoph","family":"Skudlik","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Environmental Medicine and Health Theory University of Osnabr\u00fcck  Osnabr\u00fcck Germany"},{"name":"Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm), University of Osnabr\u00fcck  Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1245-024X","authenticated-orcid":false,"given":"Richard","family":"Brans","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Environmental Medicine and Health Theory University of Osnabr\u00fcck  Osnabr\u00fcck Germany"},{"name":"Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm), University of Osnabr\u00fcck  Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4026-8728","authenticated-orcid":false,"given":"Matthias","family":"Augustin","sequence":"additional","affiliation":[{"name":"Institute for Health Services Research in Dermatology and Nursing (IVDP) University Medical Center Hamburg\u2010Eppendorf (UKE)  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9644-1278","authenticated-orcid":false,"given":"Magdalene","family":"Krensel","sequence":"additional","affiliation":[{"name":"Institute for Health Services Research in Dermatology and Nursing (IVDP) University Medical Center Hamburg\u2010Eppendorf (UKE)  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the ROQ\u2010Study 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