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They may be an overlooked cause of reactions to cosmetic products in some patients with dermatitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify naturally derived cosmetic product ingredients with allergenic potential (type I and type IV) and propose a cosmetic screening test series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was conducted in two steps. The first step was a market survey using a nonprofit application helping consumers avoid problematic substances in cosmetic products. The application contained 10\u2009067 cosmetic products that were label checked for naturally derived cosmetic product ingredients. The second step was a literature search to examine how frequently the naturally derived ingredients were described and related to allergic reactions in cosmetics or other topically administered products.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 121 different naturally derived cosmetic product ingredients that were included in at least 30 cosmetic products. In total, 22 ingredients were selected for a screening test series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We propose a supplemental patch test and a prick test screening series with naturally derived cosmetic product ingredients for patients with skin reactions to cosmetic products, aiming to identify a cause in more patients than is currently possible.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13550","type":"journal-article","created":{"date-parts":[[2020,4,5]],"date-time":"2020-04-05T08:26:06Z","timestamp":1586075166000},"page":"251-270","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Natural ingredients in cosmetic products\u2014A suggestion for a screening series for skin allergy"],"prefix":"10.1111","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4259-5711","authenticated-orcid":false,"given":"Maria A.","family":"Bruusgaard\u2010Mouritsen","sequence":"first","affiliation":[{"name":"National Allergy Research Centre Department of Dermatology and Allergy, Copenhagen University Hospital Herlev\u2010Gentofte Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3537-8463","authenticated-orcid":false,"given":"Jeanne D.","family":"Johansen","sequence":"additional","affiliation":[{"name":"National Allergy Research Centre Department of Dermatology and Allergy, Copenhagen University Hospital Herlev\u2010Gentofte Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus","family":"Zachariae","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Copenhagen University Hospital Herlev\u2010Gentofte Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christel S.","family":"Kirkeby","sequence":"additional","affiliation":[{"name":"Danish Consumer Council THINK Chemicals Danish Consumer Council Copenhagen K Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lene H.","family":"Garvey","sequence":"additional","affiliation":[{"name":"Allergy Clinic Department of Dermatology and Allergy, Copenhagen University Hospital Herlev\u2010Gentofte Hellerup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,16]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"467071","article-title":"Contact\u2010allergic reactions to cosmetics","volume":"2011","author":"Goossens A","year":"2011","journal-title":"J Allergy (Cairo)"},{"key":"e_1_2_9_3_1","unstructured":"Milj\u00f8 og f\u00f8devareministeriet. 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