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The prevalence gradually decreased thereafter, but was still high (6.5%) in 2019. Seventy\u2010three patients had clinically relevant sensitizations. MI could detect clinically relevant sensitizations in all seven patients with a negative patch test reaction to MCI\/MI 0.02%. Non\u2010occupational allergic contact dermatitis (ACD) was most frequently seen, mainly in women, with hand\/face eczema from rinse\u2010off or leave\u2010on cosmetics, such as wet wipes. Occupational ACD was mainly seen among men with airborne eczema from wall paints in house painters, or with hand eczema from hair gel\/wax in men's barbers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The prevalence of MCI\/MI and MI sensitization in Turkey following the peak in 2015 is still high. This is probably due to the currently allowed level of 100\u2009ppm for MI in rinse\u2010off cosmetics. This needs to be urgently reduced.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13656","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T07:46:12Z","timestamp":1595317572000},"page":"24-33","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Methylchloroisothiazolinone\/methylisothiazolinone and methylisothiazolinone contact allergy: A 24\u2010year, single\u2010center, retrospective cohort study from Turkey"],"prefix":"10.1111","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9585-9509","authenticated-orcid":false,"given":"Esen","family":"\u00d6zkaya","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, \u0130stanbul Faculty of Medicine \u0130stanbul University  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7484-5530","authenticated-orcid":false,"given":"S\u0131la","family":"K\u0131l\u0131\u00e7 Sayar","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, \u0130stanbul Faculty of Medicine \u0130stanbul University  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0985-5027","authenticated-orcid":false,"given":"Goncag\u00fcl","family":"Babuna Kobaner","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, \u0130stanbul Faculty of Medicine \u0130stanbul University  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5906-3976","authenticated-orcid":false,"given":"Gizem","family":"Pehlivan","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, \u0130stanbul Faculty of Medicine \u0130stanbul University  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,8,24]]},"reference":[{"issue":"2","key":"e_1_2_8_2_1","first-page":"94","article-title":"Methylisothiazolinone and isothiazolinone allergy","volume":"104","author":"Reeder M","year":"2019","journal-title":"Cutis"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2016.2951"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15267"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15602"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01634989-199009000-00003"},{"key":"e_1_2_8_7_1","unstructured":"The Cosmetics Directive of the European Union.Dir. 89\/174\/EEC. 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