{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:28:54Z","timestamp":1791332934267,"version":"4.3.1"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T00:00:00Z","timestamp":1602547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Concomitant positive patch test reactions in patients sensitized to isobornyl acrylate (IBOA) have rarely been documented.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To report concomitant sensitizations in patients with allergic contact dermatitis (ACD) from the glucose sensor FreeStyle Libre and sensitized to IBOA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 2019, 26 patients with suspected ACD from FreeStyle Libre were patch tested to a baseline series and to a (meth) acrylate series containing IBOA and 2\u2010phenoxyethyl acrylate (PEA) 0.1% pet. Diabetes devices and patch test preparations were analyzed with gas chromatography \u2013 mass spectrometry (GC\u2010MS) for the presence of IBOA and PEA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 26 patients, 18 (69%) were sensitized to IBOA, and eight (44%) and 11 (61%) of these were co\u2010sensitized to sesquiterpene lactones and fragrances, respectively. Ten patients (56%) were co\u2010sensitized to PEA, which, contrary to IBOA, could not be detected in any device. The PEA test material was shown to be contaminated with IBOA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Contact allergy to IBOA appears to be declining and IBOA\u2010sensitized patients are most often co\u2010sensitized to sesquiterpene lactones and fragrances. Vigilance is required when patch testing (acrylate) materials obtained from industry, as these might be contaminated and, hence, alter the results and their interpretation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13706","type":"journal-article","created":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T09:57:42Z","timestamp":1600855062000},"page":"166-174","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Concomitant positive patch test reactions in FreeStyle\u2010allergic patients sensitized to isobornyl acrylate"],"prefix":"10.1111","volume":"84","author":[{"given":"Ella","family":"Dendooven","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospital Antwerp (UZA)  Antwerp Belgium"},{"name":"Research Group Immunology, Infla\u2010Med Centre of Excellence University of Antwerp  Antwerp Belgium"},{"name":"Research Group Natural Products and Food \u2013 Research and Analysis 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