{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T16:45:41Z","timestamp":1780677941508,"version":"3.54.1"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T00:00:00Z","timestamp":1603324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In Sweden, cobalt chloride 0.5% has been included in the baseline series since the mid\u20101980s. A recent study from Stockholm showed that cobalt chloride 1% petrolatum (pet.) was more suitable than 0.5%. Cobalt chloride at 1.0% has been patch tested for decades in many European countries and around the world.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To study the suitability of patch testing to cobalt 1.0% vs 0.5% and to analyze the co\u2010occurrence of allergy to cobalt, chromium, and nickel.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Contact allergy to cobalt was shown in 90 patients (6.6%). Eighty (5.9%) patients tested positive to cobalt 1.0%. Thirty\u2010seven of the 90 patients (41.1%) with cobalt allergy were missed by cobalt 0.5% and 10 (0.7%) were missed by cobalt 1.0% (<jats:italic>P<\/jats:italic> &lt;\u2009.001). No case of patch test sensitization was reported. Allergy to chromium was seen in 2.6% and allergy to nickel in 13.3%. Solitary allergy to cobalt without nickel allergy was shown in 61.1% of cobalt\u2010positive individuals. Female patients had larger proportions of positive reactions to cobalt (<jats:italic>P<\/jats:italic> =\u2009.036) and nickel (<jats:italic>P<\/jats:italic> &lt;\u2009.001) than males.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results speak in favor of replacing cobalt chloride 0.5% with cobalt chloride 1.0% pet. in the Swedish baseline series, which will be done 2021.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13710","type":"journal-article","created":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T10:41:35Z","timestamp":1601462495000},"page":"153-158","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Suitable test concentration of cobalt and concomitant reactivity to nickel and chromium: A multicentre study from the Swedish Contact Dermatitis Research Group"],"prefix":"10.1111","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9005-0962","authenticated-orcid":false,"given":"Marl\u00e9ne","family":"Isaksson","sequence":"first","affiliation":[{"name":"Lund University, Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9141-9215","authenticated-orcid":false,"given":"Lina","family":"Hagvall","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg  Gothenburg Sweden"},{"name":"Department of Dermatology and Venereology Sahlgrenska University Hospital  Region V\u00e4stra G\u00f6taland, Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Glas","sequence":"additional","affiliation":[{"name":"Department of Public Health and Clinical Medicine, Dermatology and Venereology Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8506-4577","authenticated-orcid":false,"given":"Maria","family":"Lagrelius","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine Karolinska Institutet and Centre for Occupational and Environmental Medicine  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9951-5896","authenticated-orcid":false,"given":"Carola","family":"Lid\u00e9n","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaly","family":"Matura","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine Karolinska Institutet and Centre for Occupational and Environmental Medicine  Stockholm Sweden"},{"name":"Department of Dermatology Skaraborg's Hospital  Sk\u00f6vde Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3627-5124","authenticated-orcid":false,"given":"Gunnar","family":"Nyman","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg  Gothenburg Sweden"},{"name":"Department of Dermatology and Venereology Sahlgrenska University Hospital  Region V\u00e4stra G\u00f6taland, Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berndt","family":"Stenberg","sequence":"additional","affiliation":[{"name":"Department of Public Health and Clinical Medicine, Dermatology and Venereology Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Svedman","sequence":"additional","affiliation":[{"name":"Lund University, 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