{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T14:40:03Z","timestamp":1778337603013,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,3,19]],"date-time":"2021-03-19T00:00:00Z","timestamp":1616112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is controversy over late and long\u2010lasting reactions to gold sodium thiosulfate (GST).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To study the GST patch test reaction by observing the application site after 1\u00a0month, and to clarify the relevance of GST sensitization by piercings and dental metals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients<\/jats:title><jats:p>A retrospective analysis was performed on 746 patients (143 male; 603 female) who were patch tested using GST of the TRUE Test. We conducted a questionnaire on the presence of piercings or dental metals in these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The GST positive rate was 27.9% at day (D)3 and\/or D7 and 40.3% up to the 1\u2010month reading. The positive rate was significantly higher in female patients and increased with age. Sixty\u2010two percent of cases with a positive reaction at D7 continued to show a positive reaction after 1\u00a0month. Eleven percent of cases with a negative reaction at D3 and D7 showed a late reaction. Both piercings and dental metals were related to gold sensitization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The GST of the TRUE Test had a high positive and low false\u2010negative rate. The 1\u2010month reading after the patch test was important for identifying late reactions. Piercing history and dental metal were associated with gold sensitization.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13827","type":"journal-article","created":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T05:30:16Z","timestamp":1614835816000},"page":"154-163","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Multicenter 1\u2010month follow\u2010up study of the patch test reaction to the gold sodium thiosulfate of the TRUE Test and its association with piercings and dental metal history"],"prefix":"10.1111","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8367-1034","authenticated-orcid":false,"given":"Kayoko","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Allergology Fujita Health University School of Medicine  Nagoya 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