{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T08:31:48Z","timestamp":1783758708539,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T00:00:00Z","timestamp":1620000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Because <jats:italic>Myroxylon pereirae<\/jats:italic> (MP), or balsam of Peru, is nowadays almost not used \u201cas such,\u201d and fragrance mix 1 (FM1) apparently is more sensitive in detecting fragrance allergy, the usefulness of testing MP in baseline series was recently questioned.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Identification of the number of clinically relevant patch test reactions to MP not detected by FM1.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective analysis of 12\u2009030 patients patch tested with MP and FM1 for contact dermatitis between January 2018 and December 2019 in 13 Italian dermatology clinics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four hundred thirty\u2010nine patients (3.6%) had a positive patch test reaction to MP; 437 (3.6%) had a positive patch test reaction to FM1. Positive reactions to both MP and FM1 were observed in 119 subjects (1.0%), 310 (2.6%) reacted to MP only, 304 (2.5%) to FM1 only, 5 to MP and sorbitan sesquioleate (SSO), 9 to FM1 and SSO, and 5 to MP, FM1, and SSO. Single sensitizations were clinically relevant in 75.2% of cases for MP (62.9% current, 12.3% past) and 76.3% for FM1 (70.1% current, 6.2% past).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Based on our results, MP appears to be still worth testing along\u00a0with FM1 in baseline series, because it allows detection of a remarkable number of fragrance allergies, often relevant, which would be otherwise missed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13839","type":"journal-article","created":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T05:40:30Z","timestamp":1616391630000},"page":"269-273","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["<scp><i>Myroxylon pereirae<\/i><\/scp> (balsam of Peru): Still worth testing?"],"prefix":"10.1111","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0805-8496","authenticated-orcid":false,"given":"Fabrizio","family":"Guarneri","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Messina  Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2105-6217","authenticated-orcid":false,"given":"Monica","family":"Corazza","sequence":"additional","affiliation":[{"name":"Sezione di Dermatologia, Dipartimento di Scienze Mediche Universit\u00e0 degli Studi di Ferrara  Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7919-8141","authenticated-orcid":false,"given":"Luca","family":"Stingeni","sequence":"additional","affiliation":[{"name":"Dermatology Section, Department of Medicine University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8661-2822","authenticated-orcid":false,"given":"Cataldo","family":"Patruno","sequence":"additional","affiliation":[{"name":"Department of Health Sciences University Magna Graecia of Catanzaro  Catanzaro Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3309-8190","authenticated-orcid":false,"given":"Maddalena","family":"Napolitano","sequence":"additional","affiliation":[{"name":"Department of Health Sciences \"V. Tiberio\" University of Molise  Campobasso Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo D. M.","family":"Pigatto","sequence":"additional","affiliation":[{"name":"IRCCS Istituto Ortopedico Galeazzi, Department of Biomedical, Surgical and Dental Sciences University of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1735-4425","authenticated-orcid":false,"given":"Rosella","family":"Gallo","sequence":"additional","affiliation":[{"name":"Section of Dermatology \u2010 Department of Health Sciences University of Genoa, Ospedale Policlinico San Martino \u2013 IRCCS  Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0737-983X","authenticated-orcid":false,"given":"Antonio","family":"Cristaudo","sequence":"additional","affiliation":[{"name":"UOSD Dermatologia MST, Ambientale, Tropicale e Immigrazione, Istituto Dermatologico San Gallicano (IRCCS)  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5559-9722","authenticated-orcid":false,"given":"Paolo","family":"Romita","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Biomedical Science and Human Oncology University of Bari  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annamaria","family":"Offidani","sequence":"additional","affiliation":[{"name":"Clinica Dermatologica, Dipartimento di Scienze Cliniche e Molecolari Universit\u00e0 Politecnica delle Marche  Ancona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donatella","family":"Schena","sequence":"additional","affiliation":[{"name":"Section of Dermatology and Venereology, Department of Medicine University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1055-3867","authenticated-orcid":false,"given":"Nicola","family":"Milanesi","sequence":"additional","affiliation":[{"name":"Allergological and Occupational Dermatology Unit, Department of Health Sciences AUTC and University of Florence  Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Micali","sequence":"additional","affiliation":[{"name":"Dermatology Clinic University of Catania, PO G. Rodolico, AOU Policlinico\u2010Vittorio Emanuele  Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"Zucca","sequence":"additional","affiliation":[{"name":"Dermatologic clinic, University Hospital S. 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