{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T09:13:10Z","timestamp":1735809190832,"version":"3.32.0"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T00:00:00Z","timestamp":1626048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["BMBF 01ER1206","BMBF 01ER1507","BMBF 01GP1308"],"award-info":[{"award-number":["BMBF 01ER1206","BMBF 01ER1507","BMBF 01GP1308"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005626","name":"Universit\u00e4t Regensburg","doi-asserted-by":"publisher","award":["intramural funding"],"award-info":[{"award-number":["intramural funding"]}],"id":[{"id":"10.13039\/501100005626","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hand eczema (HE) is a chronic inflammatory skin disease caused by a genetic predisposition and environmental exposures. There is a lack of population\u2010based studies on skin diseases in the elderly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Our aim was to estimate the frequency of HE in the elderly to determine its burden of disease in this particular population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed data from the research platform AugUR, a study on chronic diseases in the elderly (n\u00a0=\u00a01133, ages 70\u201095 years, mean age 77.6, 45.1% women). Raw frequencies were estimated using self\u2010reports on physician\u2010diagnosed HE from a standardized personal interview. Frequencies were standardized to the Bavarian population weighted by gender and 5\u2010year age\u2010groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In our sample 2.7% (95% confidence interval [CI] 1.6\u20104.3) of the paticipants reported to ever have been diagnosed with HE. Among those 57% were male. After standardization, the frequency was estimated at 2.8% (95% CI 1.9\u20103.9). There were no differences between male and female participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared to other studies on lifetime frequency of HE, our estimates seem to be remarkably lower. More in\u2010depth studies with validated diagnoses are warranted to precisely estimate the burden of HE in the elderly.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13920","type":"journal-article","created":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T16:54:09Z","timestamp":1624467249000},"page":"489-493","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Frequency of hand eczema in the elderly: Cross\u2010sectional findings from the <scp>German AugUR<\/scp> study"],"prefix":"10.1111","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0808-1987","authenticated-orcid":false,"given":"Karl Philipp","family":"Drewitz","sequence":"first","affiliation":[{"name":"Institute of Social Medicine and Health Systems Research University of Magdeburg  Magdeburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus J.","family":"Stark","sequence":"additional","affiliation":[{"name":"Department of Genetic Epidemiology University of Regensburg  Regensburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina E.","family":"Zimmermann","sequence":"additional","affiliation":[{"name":"Department of Genetic Epidemiology University of Regensburg  Regensburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris M.","family":"Heid","sequence":"additional","affiliation":[{"name":"Department of Genetic Epidemiology University of Regensburg  Regensburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3805-8219","authenticated-orcid":false,"given":"Christian J.","family":"Apfelbacher","sequence":"additional","affiliation":[{"name":"Institute of Social Medicine and Health Systems Research University of Magdeburg  Magdeburg Germany"},{"name":"Family Medicine and Primary Care, Lee Kong Chian School of Medicine Nanyang Technological University  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700750"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12922"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2009.01669.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-010-2081-x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13804"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16248"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-019-4456-y"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700781"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16081"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16061"},{"key":"e_1_2_10_12_1","unstructured":"HeckleS.Wahrnehmung und Wissensstand zum Thema \u201echronisches Handekzem\u201d bei Betroffenen und Nicht\u2010Betroffenen [doctoral thesis]. M\u00fcnchen: Ludwig\u2010Maximilians\u2010Universit\u00e4t; 2018.http:\/\/d-nb.info\/1173087478."},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtv.2016.04.001"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-015-0122-0"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-26629-5"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00103-020-03093-z"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000012787"},{"key":"e_1_2_10_18_1","unstructured":"Bayerisches Landesamt f\u00fcr Statistik und Datenverarbeitung.Zensus 2011: Gemeindedaten Bev\u00f6lkerung Stand:09. Mai 2011. M\u00fcnchen; 2013."},{"volume-title":"Modern epidemiology","year":"2008","author":"Rothman KJ","key":"e_1_2_10_19_1"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12963"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12993"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.3876"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.13754"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.1002"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08088.x"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dys095"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12800"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0099533"},{"key":"e_1_2_10_29_1","unstructured":"BergS.Pr\u00e4valenz von Handekzemen in Heidelberg und weltweit: die Heidelberger Pr\u00e4valenzstudie im Vergleich mit Ergebnissen aus der Literatur [doctoral thesis]. Heidelberg; 2005.http:\/\/d-nb.info\/981686109."},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2001.045002099.x"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04799.x"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2006.00920.x"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.13920","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cod.13920","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.13920","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T08:44:23Z","timestamp":1735807463000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.13920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,12]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1111\/cod.13920"],"URL":"https:\/\/doi.org\/10.1111\/cod.13920","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"type":"print","value":"0105-1873"},{"type":"electronic","value":"1600-0536"}],"subject":[],"published":{"date-parts":[[2021,7,12]]},"assertion":[{"value":"2021-04-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}