{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T10:17:52Z","timestamp":1774952272536,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T00:00:00Z","timestamp":1629849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Allergic contact dermatitis from glucose sensors may interfere with their ongoing application.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate a series of Spanish patients with contact dermatitis to glucose sensors regarding former sources of contact allergens, patch test results, and outcomes from the ongoing use of the device.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A series of patients with contact dermatitis from glucose sensors was investigated in eight dermatology departments across Spain (epidemiological features, brands, latency time to develop dermatitis, the ability to continue using the devices as well as the patch test results).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty patients were evaluated (mean age 20.9\u2009years). A total of 66.7% were children and 66.7% female. Ninety per cent used Freestyle Libre (FSL). Eight of 26 (30.8%) reacted to isobornyl acrylate (IBOA) and two of 20 (10.0%) to <jats:italic>N,N<\/jats:italic> dimethylacrylamide (DMAA). The mean latency time to develop dermatitis was 9\u00a0months. Sixteen of 29 (55.2%) patients continued using the same sensor causing the reaction. Thirteen of 29 (44.8%) patients were unable to continue using the sensor because of severe reactions. Of these, five were positive to IBOA, one to IBOA and DMAA, one to DMAA, one to colophony, and one to isopropyl alcohol wipes. In one patient, the outcome was unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The frequency of sensitisation to IBOA and DMAA, was lower than in other European series, but similar to a previously published Spanish article. Legislation requiring manufacturers to provide information regarding the composition of medical devices and cooperate with the investigations into contact dermatitis is urgently needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13924","type":"journal-article","created":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T16:51:37Z","timestamp":1624985497000},"page":"554-562","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Contact dermatitis from glucose sensors in <scp>Spain<\/scp>: A multicentric approach"],"prefix":"10.1111","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8203-5834","authenticated-orcid":false,"given":"Mar\u00eda\u2010Elena","family":"Gatica\u2010Ortega","sequence":"first","affiliation":[{"name":"Dermatology Department University Hospital Complex of Toledo  Toledo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6172-9274","authenticated-orcid":false,"given":"Martin","family":"Mowitz","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University  Lund Sweden"},{"name":"Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital  Malm\u00f6 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8382-5419","authenticated-orcid":false,"given":"Mar\u00eda\u2010Antonia","family":"Pastor\u2010Nieto","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Universitario de Guadalajara  Guadalajara Spain"},{"name":"Department of Medicine and Medical Specialties, Faculty of Medicine and Health Sciences, Faculty of Medicine Alcal\u00e1 University  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5454-3671","authenticated-orcid":false,"given":"Francisco J.","family":"Navarro\u2010Trivi\u00f1o","sequence":"additional","affiliation":[{"name":"Dermatology Department University San Cecilio Hospital  Granada Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia","family":"Fern\u00e1ndez\u2010Redondo","sequence":"additional","affiliation":[{"name":"Dermatology Department Complejo Hospitalario Universitario  Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Hern\u00e1ndez\u2010Cano","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Universitario La Paz  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0199-2756","authenticated-orcid":false,"given":"Leopoldo","family":"Borrego","sequence":"additional","affiliation":[{"name":"Dermatology Department Universidad de Las Palmas de Gran Canaria  Las Palmas Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"G\u00f3mez\u2010de\u2010la\u2010Fuente","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Torralba","sequence":"additional","affiliation":[{"name":"Department of Medicine and Medical Specialties, Faculty of Medicine and Health Sciences, Faculty of Medicine Alcal\u00e1 University  Madrid Spain"},{"name":"Internal Medicine Department University Hospital of Guadalajara  Guadalajara Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4797-0269","authenticated-orcid":false,"given":"Cecilia","family":"Svedman","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University  Lund Sweden"},{"name":"Department of Occupational and Environmental Dermatology Sk\u00e5ne University Hospital  Malm\u00f6 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5434-7753","authenticated-orcid":false,"given":"Ana","family":"Gim\u00e9nez\u2010Arnau","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital del Mar, IMIM, Universitat Aut\u00f2noma de Barcelona  Barcelona 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