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This review is written in a way as to allow us to get closer to the work of the scientists in earlier days, to participate in the successes, and also to observe the weak points. The researchers concluded that the main culprit in Scandinavian turpentine was \u0394<jats:sup>3<\/jats:sup>\u2010carene hydroperoxides. This explains its high sensitizing effect compared with French turpentine which is of the Iberian type with no or only traces of \u0394<jats:sup>3<\/jats:sup>\u2010carene. Historical exposure to turpentine showed that ending the industrial exposure stopped the occupational skin sensitization. Patch test studies demonstrated that monoterpene hydroperoxides, far from being an obsolete source of contact allergy solely related to turpentine, is a common cause of contact allergy in the population. A hundred years of extensive chemical and clinical studies worldwide should be sufficient to meet the evidence requirement regarding allergic contact dermatitis caused by terpenes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13962","type":"journal-article","created":{"date-parts":[[2021,8,28]],"date-time":"2021-08-28T12:29:30Z","timestamp":1630153770000},"page":"627-636","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["One hundred years of allergic contact dermatitis due to oxidized terpenes: What we can learn from old research on turpentine allergy"],"prefix":"10.1111","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2691-3644","authenticated-orcid":false,"given":"Ann\u2010Therese","family":"Karlberg","sequence":"first","affiliation":[{"name":"Department of Chemistry and Molecular Biology University of Gothenburg  Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9507-0700","authenticated-orcid":false,"given":"Jean\u2010Pierre","family":"Lepoittevin","sequence":"additional","affiliation":[{"name":"CNRS, Institute of Chemistry UMR 7177, University of Strasbourg  Strasbourg France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,23]]},"reference":[{"issue":"4","key":"e_1_2_8_2_1","first-page":"175","article-title":"Investigations in the field of terpenes","volume":"69","author":"Widmark G","year":"1975","journal-title":"Svensk Kem Tidskr"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/tx7002239"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12127"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1997.tb00270.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2006.00939.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2012.02134.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12036"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13037"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12163"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13168"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrestox.5b00039"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-014-8066-3"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ffj.3210"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1979.tb04884.x"},{"key":"e_1_2_8_16_1","first-page":"225","volume-title":"Naval Stores. 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