{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T10:49:21Z","timestamp":1770461361949,"version":"3.49.0"},"reference-count":40,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T00:00:00Z","timestamp":1632441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008262","name":"Harboefonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008262","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007036","name":"Milj\u00f8styrelsen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007036","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Facial allergic contact dermatitis caused by cosmetic products is common. New allergens in cosmetics continuously emerge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate characteristics of patients with facial dermatitis (FD) between 2010 and 2019 including patch test results from cosmetic\u2010related allergens and a new test series with cosmetic\u2010relevant natural ingredients (CRNIs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective study analysing demographics, clinical characteristics according to MOAHLFA index (male; occupation; atopic dermatitis; hand; leg; face; age\u2009\u2265\u200940\u2009years), and patch test results to 27 cosmetic\u2010relevant allergens in FD patients. A prospective study evaluating a screening test series with CRNIs in consecutive FD patients for 1\u2009year was also conducted. These patients received a questionnaire for collecting extra characteristics (eg, concerning quality of life).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 8740 tested patients, 2292 (26.2%) had FD. Of these, 30.6% had cosmetic\u2010induced FD. The most common cosmetic\u2010related allergens were fragrances and preservatives. The most common patch test\u2010positive CRNIs were hydroperoxides of limonene and linalool, and propolis. Potato and peanut were rare, but the most common prick test\u2010positive CRNIs, however, without any relation to the use of cosmetic products. FD affected nearly all patients' quality of life and caused limitations to their daily life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Updated management and quick diagnosis of FD is important to avoid negative impact on patients' quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.13966","type":"journal-article","created":{"date-parts":[[2021,9,5]],"date-time":"2021-09-05T14:27:05Z","timestamp":1630852025000},"page":"650-659","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Facial contact dermatitis caused by cosmetic\u2010relevant allergens"],"prefix":"10.1111","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4259-5711","authenticated-orcid":false,"given":"Maria A.","family":"Bruusgaard\u2010Mouritsen","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy, National Allergy Research Centre, Herlev and Gentofte Hospital University of Copenhagen  Hellerup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lene H.","family":"Garvey","sequence":"additional","affiliation":[{"name":"Allergy Clinic, Department of Dermatology and Allergy Herlev and Gentofte Hospital  Hellerup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Hellerup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3537-8463","authenticated-orcid":false,"given":"Jeanne D.","family":"Johansen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, National Allergy Research Centre, Herlev and Gentofte Hospital University of Copenhagen  Hellerup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,24]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Glasser HeedeN. 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