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Against this background, this systematic review aims to compile and appraise evidence regarding skin toxicity of 2\u2010hydroxyethyl methacrylate (HEMA; CAS no. 212\u2010782\u20102) and ethyl cyanoacrylate (ECA; CAS no. 7085\u201085\u20100) contained in cosmetic glues used among hairdressers and beauticians who perform nail treatments and eyelash extension as well as hair extension applications. This systematic review followed the Preferred Reporting Items for Systematic review and Meta\u2010Analysis (PRISMA) 2020 recommendations for reporting systematic reviews and meta\u2010analysis. In total, six publications from six countries were eligible for this systematic review. A meta\u2010analysis revealed that hairdressers and beauticians have a ninefold increased risk of developing contact allergy to HEMA compared with controls who are not hairdressers and beauticians. Results for ECA are lacking. The results of this systematic review clearly show that\u2014regarding contact allergy to acrylates\u2014it is not appropriate to apply risk assessment for consumers to hairdressers and beauticians who occupationally handle cosmetic glues. The regulations in existence do not adequately address occupational risks for hairdressers and beauticians connected with the use of acrylate\u2010containing cosmetic substances and need reconsideration.<\/jats:p>","DOI":"10.1111\/cod.14056","type":"journal-article","created":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T13:24:15Z","timestamp":1643376255000},"page":"480-492","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Allergic contact dermatitis caused by 2\u2010hydroxyethyl methacrylate and ethyl cyanoacrylate contained in cosmetic glues among hairdressers and beauticians who perform nail treatments and eyelash extension as well as hair extension applications: A systematic review"],"prefix":"10.1111","volume":"86","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4090-6726","authenticated-orcid":false,"given":"Cara","family":"Symanzik","sequence":"first","affiliation":[{"name":"Department of 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