{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T21:27:17Z","timestamp":1793050037752,"version":"4.5.0"},"reference-count":198,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T00:00:00Z","timestamp":1647216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The literature on positive patch\u2010test results in acute generalized exanthematous pustulosis (AGEP) is reviewed. Ninety\u2010three drugs were identified that have together caused 259 positive patch tests in 248 patients with AGEP. The drug classes causing the highest number of reactions are beta\u2010lactam antibiotics (25.9%), other antibiotics (20.8%), iodinated contrast media (7.3%), and corticosteroids (5.4%), together accounting for nearly 60% of all reactions. The highest number of reactions to individual drugs was to amoxicillin (n\u00a0=\u00a036), followed by pristinamycin (n\u00a0=\u00a025), diltiazem (n\u00a0=\u00a014), amoxicillin\u2010clavulanic acid (n\u00a0=\u00a013), clindamycin (n\u00a0=\u00a011), and iomeprol (n\u00a0=\u00a08); 59 of the 93 drugs each caused a single case only. The \u201cTop\u201010\u201d drugs together caused over 50% of all reactions. The sensitivity of patch testing (percentage of positive reactions) in patients with AGEP is largely unknown, but may generally be ~50%, which also applies to pristinamycin. Patch testing in AGEP appears to be safe, although mild recurrence of AGEP skin symptoms or other rashes may occur occasionally. Clinical aspects of AGEP, including epidemiology, etiology and pathophysiology, clinical features, histology, treatment, and prognosis are briefly presented, as are diagnosing the disease and identifying the culprit drugs with patch tests, intradermal tests, in vitro tests, and challenge tests.<\/jats:p>","DOI":"10.1111\/cod.14075","type":"journal-article","created":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T06:44:20Z","timestamp":1645425860000},"page":"119-141","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Results of patch testing in acute generalized exanthematous pustulosis (<scp>AGEP<\/scp>): A literature review"],"prefix":"10.1111","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6666-7292","authenticated-orcid":false,"given":"Anton C.","family":"de Groot","sequence":"first","affiliation":[{"name":"Dermatologist np Wapserveen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14090"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.07.017"},{"issue":"3","key":"e_1_2_8_4_1","first-page":"210","article-title":"Akute lokalisierte exanthematische Pustulose (ALEP) [acute localized exanthematous pustulosis (ALEP)]","volume":"3","author":"Prange B","year":"2005","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17081214"},{"key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1201\/9781003158004","volume-title":"Monographs in Contact Allergy, Volume 4. Systemic Drugs","author":"De Groot AC","year":"2022"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1968.tb11947.x"},{"issue":"1","key":"e_1_2_8_8_1","first-page":"37","article-title":"Pustuloses exanth\u00e9matiques aigu\u00ebs g\u00e9n\u00e9ralis\u00e9es, \u00e0 propos de 4 cas","volume":"107","author":"Beylot C","year":"1980","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-019-00825-2"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30378-6"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.5414\/ALX01508E"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612822666160928125152"},{"issue":"7","key":"e_1_2_8_13_1","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/ddg.12747","article-title":"Severe drug\u2010induced skin reactions: clinical features, diagnosis, etiology, and therapy","volume":"13","author":"Paulmann M","year":"2015","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-013-2698-7"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.12788\/j.sder.0057"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000335625"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2010.04.004"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2010.0932"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0b013e32832cf64e"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08156.x"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0000000000000546"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12502"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09967.x"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2010.01612.x"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0560.2001.028003113.x"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-014-0442-8"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1996.tb02364.x"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12125"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000839"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2020.07.005"},{"issue":"1","key":"e_1_2_8_31_1","first-page":"15","article-title":"Testing for drug hypersensitivity syndromes","volume":"34","author":"Rive CM","year":"2013","journal-title":"Clin Biochem Rev"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.10.030"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612825666191107104126"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2018.09.014"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2020.00156"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12142"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2021.02.060"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12350"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12886"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.2003.00279.x"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-017-0206-1"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.15087"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13076"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.20-0138"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.12734"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.07.033"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.18176\/jiaci.0181"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13790"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15274"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0616"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1080\/000155598441594"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsi.2015.04.007"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.9.1181"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1159\/000350939"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e31824a603d"},{"issue":"6","key":"e_1_2_8_56_1","first-page":"860","article-title":"Acute generalized exanthematous pustulosis secondary to acyclovir confirmed by positive patch testing","volume":"96","author":"Kubin ME","year":"2016","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15986"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12842"},{"issue":"3","key":"e_1_2_8_59_1","first-page":"209","article-title":"A twin case of acute juvenile generalized pustular psoriasis accompanied by generalized exanthematous pustulosis (AGEP)","volume":"11","author":"Watanabe A","year":"2012","journal-title":"Skin Res"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.14146"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2019.05.049"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1159\/000480700"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1177\/1203475417701421"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-006-1161-4"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12720"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI12118"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2000.00592.x"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.allerg.2004.02.001"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1177\/1203475415588003"},{"issue":"5","key":"e_1_2_8_70_1","first-page":"178","article-title":"A case of acute generalized exanthematous pustulosis due to amoxicillin\u2010clavulanate with multiple positivity to beta\u2010lactam patch testing","volume":"45","author":"Bomarrito L","year":"2013","journal-title":"Eur Ann Allergy Clin Immunol"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000502"},{"issue":"6","key":"e_1_2_8_72_1","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1684\/ejd.2018.3467","article-title":"Cutaneous drug reactions: acute rash with pinhead\u2010sized pustules","volume":"28","author":"Hern\u00e1ndez\u2010Arag\u00fc\u00e9s I","year":"2018","journal-title":"Eur J Dermatol"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.12809\/hkmj198263"},{"issue":"3","key":"e_1_2_8_74_1","first-page":"124","article-title":"Acute generalized exanthematic pustulosis (AGEP).One case report [Pustulose exanthematique aigue generalisee. A propos d'un cas]","volume":"17","author":"Buffiere I","year":"1998","journal-title":"Nouvelles Dermatologiques"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2001.44020916.x"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.2500\/aap.2021.42.200110"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2006.00929.x"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2019.09.024"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2008.00484.x"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2010.02377.x"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2010.1205"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1998.tb02467.x"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000302"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2014.08.003"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13451"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546630410033763"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13875"},{"issue":"12","key":"e_1_2_8_88_1","first-page":"1136","article-title":"Anticonvulsant hypersensitivity syndrome with severe repercussions in the skin and kidneys","volume":"38","author":"Duran\u2010Ferreras E","year":"2004","journal-title":"Rev Neurol"},{"issue":"6","key":"e_1_2_8_89_1","first-page":"260","article-title":"Acute generalized exanthematous pustulosis (AGEP): confirmation by in vivo patch and prick tests","volume":"74","author":"Haskova M","year":"1999","journal-title":"Cesko\u2010Slovenska Dermatol"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0151-9638(06)77607-4"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.2174\/1574886315999200729144555"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-8206.2009.00794.x"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr.06.2008.0343"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13838"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.5114\/pdia.2014.40938"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13857"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2011.23.S3.S380"},{"issue":"7","key":"e_1_2_8_98_1","first-page":"555","article-title":"Acute generalized exanthematous pustulosis caused by celecoxib","volume":"103","author":"Yang CC","year":"2004","journal-title":"J Formos Med Assoc"},{"issue":"11","key":"e_1_2_8_99_1","first-page":"1051","article-title":"Severe cutaneous drug reactions to celecoxib (Celebrex)","volume":"130","author":"Marques S","year":"2003","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_8_100_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13443"},{"key":"e_1_2_8_101_1","doi-asserted-by":"publisher","DOI":"10.1080\/000155599750010571"},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.1159\/000087024"},{"issue":"2","key":"e_1_2_8_103_1","first-page":"155","article-title":"Pustular psoriasis and drug\u2010induced pustulosis","volume":"146","author":"Serra D","year":"2011","journal-title":"G Ital Dermatol Venereol"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2006.02402.x"},{"key":"e_1_2_8_105_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13796"},{"issue":"10","key":"e_1_2_8_106_1","first-page":"421","article-title":"Clindamycin\u2010induced acute generalised exanthematous pustulosis: five cases and a review of the literature","volume":"74","author":"Smeets TJ","year":"2016","journal-title":"Neth J Med"},{"key":"e_1_2_8_107_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13575"},{"key":"e_1_2_8_108_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2003.00031.x"},{"key":"e_1_2_8_109_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16738"},{"key":"e_1_2_8_110_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31827a0c46"},{"issue":"5","key":"e_1_2_8_111_1","first-page":"546","article-title":"A case of acute generalized exanthematous pustulosis (AGEP) with acute kidney injury","volume":"8","author":"Yamamoto A","year":"2009","journal-title":"Skin Res"},{"key":"e_1_2_8_112_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02313.x"},{"key":"e_1_2_8_113_1","doi-asserted-by":"publisher","DOI":"10.1159\/000246204"},{"key":"e_1_2_8_114_1","doi-asserted-by":"publisher","DOI":"10.1080\/000155500750043122"},{"key":"e_1_2_8_115_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13554"},{"issue":"3","key":"e_1_2_8_116_1","first-page":"765","article-title":"Acute generalized exanthematous pustulosis due to diltiazem: investigation of cross\u2010reactivity with other calcium channel blockers","volume":"4","author":"Santa S","year":"2016","journal-title":"J Allergy Clin Immunol Pract"},{"key":"e_1_2_8_117_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.dad.0000160982.75176.6c"},{"issue":"3","key":"e_1_2_8_118_1","first-page":"274","article-title":"Acute generalized exanthematous pustulosis induced by diltiazem: value of patch testing","volume":"197","author":"Jan V","year":"1998","journal-title":"Dermatology"},{"key":"e_1_2_8_119_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1997.tb01139.x"},{"key":"e_1_2_8_120_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1995.tb01339.x"},{"issue":"1","key":"e_1_2_8_121_1","first-page":"99","article-title":"Acute generalized exanthematous pustulosis associated with diltiazem","volume":"21","author":"Serr\u00e3o V","year":"2008","journal-title":"Acta Med Port"},{"issue":"10","key":"e_1_2_8_122_1","first-page":"251","article-title":"Pustular reaction induced by diltiazem HCl","volume":"33","author":"Nishiimura T","year":"1991","journal-title":"Skin Res"},{"key":"e_1_2_8_123_1","article-title":"Int\u00e9ret des \u00e9picutan\u00e9s dans !es toxicodermies graves","volume":"53","author":"Wolkenstein P","year":"1995","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_8_124_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2004.tb00595.x"},{"issue":"4","key":"e_1_2_8_125_1","first-page":"200","article-title":"Eprazinonexanthem mit subkornealer Pustelbildung [Eprazinone exanthema with subcorneal pustulosis]","volume":"35","author":"Faber M","year":"1984","journal-title":"Hautarzt"},{"key":"e_1_2_8_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2013.05.015"},{"key":"e_1_2_8_127_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1995.tb01593.x"},{"key":"e_1_2_8_128_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0381"},{"key":"e_1_2_8_129_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13152"},{"issue":"2","key":"e_1_2_8_130_1","first-page":"212","article-title":"Fluconazole\u2010induced acute generalized exanthematous pustulosis","volume":"60","author":"Di Lernia V","year":"2015","journal-title":"Indian J Dermatol"},{"key":"e_1_2_8_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2007.07.004"},{"issue":"12","key":"e_1_2_8_132_1","first-page":"1146","article-title":"Pustulose exanth\u00e9matique aigu\u00eb g\u00e9n\u00e9ralis\u00e9e \u00e0 la fluindione avec atteinte r\u00e9nale","volume":"130","author":"Thurot C","year":"2003","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_8_133_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12878"},{"key":"e_1_2_8_134_1","doi-asserted-by":"publisher","DOI":"10.4103\/0253-7613.169589"},{"key":"e_1_2_8_135_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13841"},{"key":"e_1_2_8_136_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.13513"},{"key":"e_1_2_8_137_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.15419"},{"key":"e_1_2_8_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.05.041"},{"issue":"5","key":"e_1_2_8_139_1","article-title":"Acute generalized exanthematous pustulosis (AGEP) caused: a case series and review of the guidelines for patch testing in cutaneous drug eruptions","volume":"27","author":"O'Toole AC","year":"2017","journal-title":"Dermatitis"},{"issue":"4","key":"e_1_2_8_140_1","article-title":"Acute generalized exanthematous pustulosis caused by Atarax\u00ae in a sensitized patient","volume":"24","author":"Lacroix J","year":"2013","journal-title":"Dermatitis"},{"key":"e_1_2_8_141_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08225.x"},{"issue":"2","key":"e_1_2_8_142_1","first-page":"97","article-title":"Hydroxyzine pamoate\u2010induced acute generalized exanthematous pustulosis (AGEP) followed by Psoriasis vulgaris","volume":"42","author":"Utida T","year":"2010","journal-title":"Eur Ann allergy Clin Immunol"},{"issue":"1","key":"e_1_2_8_143_1","first-page":"26","article-title":"A case of acute generalized exanthematous pustulosis due to hydroxyzine pamoate","volume":"4","author":"Yasugi Y","year":"2005","journal-title":"Skin Res"},{"key":"e_1_2_8_144_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12978"},{"key":"e_1_2_8_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2014.07.015"},{"key":"e_1_2_8_146_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12724"},{"key":"e_1_2_8_147_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13242"},{"key":"e_1_2_8_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2020.08.006"},{"issue":"1","key":"e_1_2_8_149_1","first-page":"66","article-title":"First case report of acute generalized exanthematous pustulosis due to intravenous iopromide","volume":"24","author":"Bavbek S","year":"2014","journal-title":"J Investig Allergol Clin Immunol"},{"key":"e_1_2_8_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2010.06.018"},{"key":"e_1_2_8_151_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1996.tb02666.x"},{"key":"e_1_2_8_152_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1985.tb02328.x"},{"issue":"2","key":"e_1_2_8_153_1","first-page":"148","article-title":"First case report of acute generalized exanthematous pustulosis due to labetalol","volume":"25","author":"G\u00f3mez Torrijos E","year":"2015","journal-title":"J Investig Allergol Clin Immunol"},{"issue":"3","key":"e_1_2_8_154_1","doi-asserted-by":"crossref","first-page":"250","DOI":"10.2340\/0001555577250","article-title":"Acute generalized exanthematous pustulosis induced by lansoprazole","volume":"77","author":"Dewerdt S","year":"1997","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_8_155_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2005.tb00875.x"},{"key":"e_1_2_8_156_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2003.0120h.x"},{"issue":"2","key":"e_1_2_8_157_1","first-page":"234","article-title":"Acute generalized exanthematous pustulosis due to meladinine with positive patch tests","volume":"129","author":"Morant C","year":"2002","journal-title":"Ann Dermatol Venereol"},{"issue":"3","key":"e_1_2_8_158_1","first-page":"241","article-title":"Methylprednisolone\u2010induced acute generalized exanthematous pustulosis","volume":"128","author":"Mussot\u2010Chia C","year":"2001","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_8_159_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.135.1.93"},{"key":"e_1_2_8_160_1","doi-asserted-by":"publisher","DOI":"10.1097\/01206501-199906000-00044"},{"key":"e_1_2_8_161_1","doi-asserted-by":"publisher","DOI":"10.1097\/01206501-199803000-00043"},{"issue":"5","key":"e_1_2_8_162_1","first-page":"469","article-title":"Acute exanthematous pustular drug eruption induced by mexiletine","volume":"11","author":"Sasaki K","year":"2001","journal-title":"Eur J Dermatol"},{"key":"e_1_2_8_163_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13773"},{"issue":"1","key":"e_1_2_8_164_1","first-page":"61","article-title":"The interest of cooperation between clinician, allergologist and pharmacovigilance center: severe toxidermia complicated by myopericarditis induced by miconazole oral gel","volume":"27","author":"Tetart F","year":"2013","journal-title":"Fund Clin Pharmacol"},{"issue":"2","key":"e_1_2_8_165_1","doi-asserted-by":"crossref","first-page":"168","DOI":"10.2340\/0001555577168169","article-title":"Minocycline\u2010induced acute generalized exanthematous pustulosis in a patient with generalized pustular psoriasis showing elevated level of sELAM\u20101","volume":"77","author":"Yamamoto T","year":"1997","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_8_166_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.02.032"},{"key":"e_1_2_8_167_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000573"},{"key":"e_1_2_8_168_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1997.tb00010.x"},{"issue":"4","key":"e_1_2_8_169_1","first-page":"273","article-title":"Pustulose exanth\u00e9matique aig\u00fce generalis\u00e9e li\u00e9e \u00e0 la buph\u00e9nine: un cas","volume":"119","author":"Spindler E","year":"1992","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_8_170_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1997.19582038.x"},{"key":"e_1_2_8_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2012.01.022"},{"issue":"4","key":"e_1_2_8_172_1","first-page":"439","article-title":"Acute generalized exanthematous pustulosis induced by drugs with low\u2010digestive absorption: acarbose and nystatin","volume":"130","author":"Poszepczynska\u2010Guigne E","year":"2003","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_8_173_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13994"},{"key":"e_1_2_8_174_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13005"},{"key":"e_1_2_8_175_1","doi-asserted-by":"publisher","DOI":"10.1159\/000092837"},{"key":"e_1_2_8_176_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12658"},{"key":"e_1_2_8_177_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2021.3981"},{"key":"e_1_2_8_178_1","doi-asserted-by":"publisher","DOI":"10.1177\/1352458508097218"},{"key":"e_1_2_8_179_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08594.x"},{"key":"e_1_2_8_180_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1999.tb06018.x"},{"key":"e_1_2_8_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2019.06.009"},{"key":"e_1_2_8_182_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1995.tb00553.x"},{"issue":"26","key":"e_1_2_8_183_1","first-page":"215","article-title":"Disseminated acute pustulosis from pseudoephedrine","volume":"50","author":"Moraga M","year":"1995","journal-title":"Allergy"},{"key":"e_1_2_8_184_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0108"},{"key":"e_1_2_8_185_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.05717.x"},{"key":"e_1_2_8_186_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2002.470308_1.x"},{"key":"e_1_2_8_187_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.15431"},{"key":"e_1_2_8_188_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2003.0120g.x"},{"key":"e_1_2_8_189_1","doi-asserted-by":"publisher","DOI":"10.1272\/jnms.78.329"},{"issue":"7","key":"e_1_2_8_190_1","first-page":"339","article-title":"Acute generalized exanthematic pustulosis induced by spiramycin: usefulness of patch testing","volume":"94","author":"Kastalli S","year":"2016","journal-title":"Tunis Med"},{"key":"e_1_2_8_191_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.14259"},{"key":"e_1_2_8_192_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)70191-9"},{"issue":"2","key":"e_1_2_8_193_1","first-page":"119","article-title":"Acute generalized exanthematous pustulosis due to tetrazepam","volume":"18","author":"Thomas E","year":"2008","journal-title":"J Investig Allergol Clin Immunol"},{"key":"e_1_2_8_194_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03390.x"},{"issue":"11","key":"e_1_2_8_195_1","first-page":"35","article-title":"A case of vancomycin\u2010induced acute generalized exanthematous pustulosis confirmed by patch testing","volume":"13","author":"Pettit C","year":"2020","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_8_196_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2005.10.030"},{"key":"e_1_2_8_197_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12867"},{"issue":"1","key":"e_1_2_8_198_1","first-page":"47","article-title":"Tests cutan\u00e9s dans l'exploration des toxidermies suppos\u00e9es de m\u00e9canisme immuno\u2010allergique","volume":"184","author":"Barbaud A","year":"2000","journal-title":"Bull Acad Natl Med"},{"key":"e_1_2_8_199_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1085-5629(96)80037-X"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14075","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cod.14075","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14075","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T20:43:28Z","timestamp":1700253808000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.14075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,14]]},"references-count":198,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1111\/cod.14075"],"URL":"https:\/\/doi.org\/10.1111\/cod.14075","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,14]]},"assertion":[{"value":"2022-01-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}