{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T10:49:44Z","timestamp":1782125384655,"version":"3.54.5"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T00:00:00Z","timestamp":1650326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The practical importance of two recently described epoxy hardener allergens\u20141,3\u2010benzenedimethanamine, <jats:italic>N<\/jats:italic>\u2010(2\u2010phenylethyl) derivatives (1,3\u2010BDMA\u2010D) and hydrogenated formaldehyde benzenamine polymer (FBAP)\u2014as occupational allergens remains to be defined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe patients diagnosed at the Finnish Institute of Occupational Health (FIOH) with positive reactions to 1,3\u2010BDMA\u2010D or FBAP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We searched FIOH's patch\u2010test files from January 2017 to December 2020 for patients examined due to suspected occupational contact allergy to epoxy compounds. We analyzed the patch\u2010test results and sources of exposure to various epoxy hardeners and focused on occupations, symptoms, and the sources of exposure to 1,3\u2010BDMA\u2010D and FBAP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period, 102 patients were examined at FIOH for suspected occupational contact allergy to epoxy compounds. Of these, 19 (19%) were diagnosed with contact allergy to 1,3\u2010BDMA\u2010D (<jats:italic>n<\/jats:italic>\u00a0=\u200910) or FBAP (<jats:italic>n<\/jats:italic>\u00a0=\u200912). The largest occupational group was sewage pipe reliners (<jats:italic>n<\/jats:italic>\u00a0=\u20098). Seven different hardener products contained FBAP, whereas 1,3\u2010BDMA\u2010D was present in only one hardener used by spray painters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A substantial number of patients with suspected occupational epoxy resin system allergy tested positive to in\u2010house test substances of 1,3\u2010BDMA\u2010D and\/or FBAP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.14109","type":"journal-article","created":{"date-parts":[[2022,3,16]],"date-time":"2022-03-16T07:35:28Z","timestamp":1647416128000},"page":"81-88","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Characterization of patients with occupational allergy to two new epoxy hardener compounds"],"prefix":"10.1111","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3711-6846","authenticated-orcid":false,"given":"Sari","family":"Suomela","sequence":"first","affiliation":[{"name":"Occupational Medicine Finnish Institute of Occupational Health (FIOH)  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0356-7064","authenticated-orcid":false,"given":"Maria","family":"Pesonen","sequence":"additional","affiliation":[{"name":"Occupational Medicine Finnish Institute of Occupational Health (FIOH)  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katriina","family":"Ylinen","sequence":"additional","affiliation":[{"name":"Work Environment Laboratories Finnish Institute of Occupational Health (FIOH)  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5595-5512","authenticated-orcid":false,"given":"Kristiina","family":"Aalto\u2010Korte","sequence":"additional","affiliation":[{"name":"Occupational Medicine Finnish Institute of Occupational Health (FIOH)  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1353-121X","authenticated-orcid":false,"given":"Katri","family":"Suuronen","sequence":"additional","affiliation":[{"name":"Occupational Medicine Finnish Institute of Occupational Health (FIOH)  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12445"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12491"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12490"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12280"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12652"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12835"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12475"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12432"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13488"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100536.2011.02028.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12529"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13122"},{"key":"e_1_2_8_14_1","unstructured":"The Finnish Chemical Product Register.http:\/\/www.kemidigi.fi"},{"key":"e_1_2_8_15_1","unstructured":"European CHemicals Agency (ECHA). Available athttps:\/\/echa.europa.eu\/de\/registration-dossier\/-\/registered-dossier\/5561(last accessed in February2022)."},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100536.2011.02049.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-68617-2_51"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-68617-2_17"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12455"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14109","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cod.14109","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T10:54:32Z","timestamp":1692874472000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.14109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,19]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1111\/cod.14109"],"URL":"https:\/\/doi.org\/10.1111\/cod.14109","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,19]]},"assertion":[{"value":"2022-01-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}