{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:46:46Z","timestamp":1790520406233,"version":"4.1.0"},"reference-count":9,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T00:00:00Z","timestamp":1649980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>The repeated open application test (ROAT) is an adjuvant investigation measure to patch testing in the diagnosis of allergic contact dermatitis. ESCD recommends a 15\u2009days duration but its overall duration varies according to publications and patients hardly adhere to prolonged ROAT duration beyond 1\u2009week.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>The Dermatology and Allergy Group of the French Society of Dermatology performed a prospective study with the aim of determining the best duration for the ROAT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 328 ROAT results were collected for topical products, including cosmetics (60%) and topical medications (31.1%). Fifty\u2010nine (18%) ROATs were positive, and 16 (5%) were doubtful. All the positive ROATs occurred within 10\u2009days, with a median time to positivity of 3\u2009days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>According to our results, a minimum duration of 10\u2009days is necessary to achieve a positive ROAT to a topical product.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cod.14118","type":"journal-article","created":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T04:24:15Z","timestamp":1649132655000},"page":"170-175","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["What is the optimal duration for a\n                    <scp>ROAT<\/scp>\n                    ? The experience of the French Dermatology and Allergology group (\n                    <scp>DAG<\/scp>\n                    )"],"prefix":"10.1111","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5011-8056","authenticated-orcid":false,"given":"Emmanuelle","family":"Amsler","sequence":"first","affiliation":[{"name":"Service de dermatologie et allergologie H\u00f4pital Tenon  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haudrey","family":"Assier","sequence":"additional","affiliation":[{"name":"Service de Dermatologie H\u00f4pital Henri Mondor  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e8le","family":"Soria","sequence":"additional","affiliation":[{"name":"Service de dermatologie et allergologie H\u00f4pital Tenon  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corina","family":"Bara","sequence":"additional","affiliation":[{"name":"Service de dermatologie, Centre Hospitalier Le Mans  Le Mans France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2540-4349","authenticated-orcid":false,"given":"Marie Christine","family":"Ferrier le Bou\u00ebdec","sequence":"additional","affiliation":[{"name":"Service de dermatologie CHU Clermont\u2010Ferrand, Universit\u00e9 Clermont Auvergne  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8889-1589","authenticated-orcid":false,"given":"Annick","family":"Barbaud","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, Institut Pierre Louis d'Epid\u00e9miologie et de Sant\u00e9 Publique, AP\u2010HP. Sorbonne Universit\u00e9, H\u00f4pital Tenon D\u00e9partement de dermatologie et allergologie  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3679-6613","authenticated-orcid":false,"given":"Brigitte","family":"Milpied","sequence":"additional","affiliation":[{"name":"Service de Dermatologie H\u00f4pital St Andr\u00e9  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Giordano\u2010Labadie","sequence":"additional","affiliation":[{"name":"Service de Dermatologie H\u00f4pital Larrey, CHU Toulouse  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine","family":"Pasteur","sequence":"additional","affiliation":[{"name":"Service de dermatologie, CHU Clermont\u2010Ferrand Universit\u00e9 Clermont Auvergne  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Badaoui","sequence":"additional","affiliation":[{"name":"Service de dermatologie H\u00f4pital d'Instruction des Arm\u00e9es B\u00e9gin  St Mand\u00e9 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1778-9904","authenticated-orcid":false,"given":"Aude","family":"Valois","sequence":"additional","affiliation":[{"name":"Service de Dermatologie H\u00f4pital d'Instruction des Arm\u00e9es Sainte Anne 2 boulevard Sainte Anne  Toulon Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Castelain","sequence":"additional","affiliation":[{"name":"Service de Dermatologie CHU Besan\u00e7on  Besan\u00e7on France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9969-2462","authenticated-orcid":false,"given":"Flore","family":"Kurihara","sequence":"additional","affiliation":[{"name":"Service de dermatologie et allergologie H\u00f4pital Tenon  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Castagna","sequence":"additional","affiliation":[{"name":"Service de dermatologie et allergologie H\u00f4pital Tenon  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Boulard","sequence":"additional","affiliation":[{"name":"Service de dermatologie, Groupe hospitalier du Havre  Le Havre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Bernier","sequence":"additional","affiliation":[{"name":"Service de dermatologie CHU H\u00f4tel Dieu  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Leleu","sequence":"additional","affiliation":[{"name":"Service de Dermatologie CHU Fran\u00e7ois Mitterrand  Dijon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5997-1181","authenticated-orcid":false,"given":"Pierre","family":"Marcant","sequence":"additional","affiliation":[{"name":"Service de dermatologie, Centre hospitalier universitaire de Lille  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9824-1034","authenticated-orcid":false,"given":"Marie Noelle","family":"Cr\u00e9py","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Diseases University Hospital of Centre of Paris, Hotel\u2010Dieu Hospital  Paris France"},{"name":"Department of Dermatology University Hospital of Centre of Paris, Cochin Hospital  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Tetart","sequence":"additional","affiliation":[{"name":"Centre Erik Satie Allergologie Rouen University Hospital  Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7991-3165","authenticated-orcid":false,"given":"Nadia","family":"Raison\u2010Peyron","sequence":"additional","affiliation":[{"name":"Service de Dermatologie H\u00f4pital Saint Eloi, CHU Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"from the Dermatology and Allergy Group of the French Society of Dermatology 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