{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T13:49:08Z","timestamp":1783950548482,"version":"3.55.0"},"reference-count":49,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T00:00:00Z","timestamp":1651104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Contact allergy and atopic dermatitis (AD) are both common inflammatory T cell\u2010mediated diseases and many factors may influence the prevalence of contact allergy in AD patients. In children, their possible correlation was debated with conflicting results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The present study aimed to assess the prevalence of contact sensitivity in children and to investigate the association with AD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>A retrospective multicentre study on children aged from 0 to 14\u2009years patch tested between January 2017 and December 2018 was performed. Children were consecutively patch tested with the SIDAPA (Societ\u00e0 Italiana Dermatologia Allergologica Professionale Ambientale) baseline series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 432 children investigated for contact allergy, 125 (28.9%) showed a positive reaction to at least one of the allergens tested, with a higher prevalence of positive patch test reactions in girls (32.3%) than in boys (25.0%). The most frequent contact allergens were nickel sulphate (10.2%), cobalt chloride (6.7%), methylisothiazolinone (3.7%), fragrance mix\u20102 (3.2%), potassium dichromate (2.8%), fragrance mix\u20101 (2.1%) and methylchloroisothiazolinone\/methylisothiazolinone (2.1%). One\u2010hundred\u2010three children (23.8%) suffered from AD showing a higher prevalence of positive patch test (36.9%) compared to children without AD (26.4%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Despite the topic being still controversial, the present study suggests a consistent prevalence of contact allergy among children with higher sensitivity rate among children with AD than without AD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.14130","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T04:03:15Z","timestamp":1650600195000},"page":"265-272","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Contact allergy in children with and without atopic dermatitis: An Italian multicentre study"],"prefix":"10.1111","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1319-4946","authenticated-orcid":false,"given":"Domenico","family":"Bonamonte","sequence":"first","affiliation":[{"name":"Section of Dermatology, Department of Biomedical Science and Human Oncology University of Bari \u201cAldo Moro\u201d Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6674-4278","authenticated-orcid":false,"given":"Katharina","family":"Hansel","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Medicine and Surgery University of Perugia Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Romita","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Biomedical Science and Human Oncology University of Bari \u201cAldo Moro\u201d Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5791-0775","authenticated-orcid":false,"given":"Anna Belloni","family":"Fortina","sequence":"additional","affiliation":[{"name":"Unit of Pediatric Dermatology, Department of Medicine DIMED University of Padua Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giampiero","family":"Girolomoni","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Medicine University of Verona Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Fabbrocini","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery University of Naples Federico II Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cataldo","family":"Patruno","sequence":"additional","affiliation":[{"name":"Department of Health Sciences University Magna Graecia of Catanzaro Catanzaro Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maddalena","family":"Napolitano","sequence":"additional","affiliation":[{"name":"Department of Medicine and Health Sciences Vincenzo Tiberio University of Molise Campobasso Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Patrizi","sequence":"additional","affiliation":[{"name":"Unit of Dermatology IRCCS Azienda Ospedaliero Universitaria, University of Bologna Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Argenziano","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine University of Campania Luigi Vanvitelli Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5157-3939","authenticated-orcid":false,"given":"Giuseppe","family":"Micali","sequence":"additional","affiliation":[{"name":"Dermatology Clinic University of Catania Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piergiacomo","family":"Calzavara Pinton","sequence":"additional","affiliation":[{"name":"Dermatology Department University of Brescia Brescia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6196-9788","authenticated-orcid":false,"given":"Caterina","family":"Foti","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Biomedical Science and Human Oncology University of Bari \u201cAldo Moro\u201d Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7919-8141","authenticated-orcid":false,"given":"Luca","family":"Stingeni","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Medicine and Surgery University of Perugia Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Italian Society of Dermatology and Venereology, Pediatric Dermatology Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.01963.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13975"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000214"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/pai.12397"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000083"},{"issue":"5","key":"e_1_2_8_7_1","first-page":"300","article-title":"Allergic contact dermatitis in early infancy","volume":"54","author":"Fisher AA","year":"1994","journal-title":"Cutis"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2008.07099"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12873"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2012.06.048"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e318273a3e0"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15628"},{"issue":"5","key":"e_1_2_8_13_1","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1684\/ejd.2018.3422","article-title":"Clinical characteristics and genetic variation in atopic dermatitis patients with and without allergic contact dermatitis","volume":"28","author":"Lee S","year":"2018","journal-title":"Eur J Dermatol"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-018-8711-2"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2016.6136"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.02.001"},{"key":"e_1_2_8_17_1","first-page":"15","article-title":"Contact dermatitis in pediatric age","volume":"39","author":"Bonamonte D","year":"2004","journal-title":"G Ital Dermatol Venereol"},{"issue":"1","key":"e_1_2_8_18_1","first-page":"1","article-title":"Dermatite allergica da contatto in et\u00e0 pediatrica","volume":"64","author":"Bonamonte D","year":"2010","journal-title":"Ann Ital Dermatol Allergol"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.2174\/1871530319666190211123342"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.03.012"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14737"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000037"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12711"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1973.01620170029009"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1975.tb05437.x"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1989.01670150056006"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15065"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12358"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.07.066"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2011.05.010"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2011.07.025"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.11.002"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.3046"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2009.08081"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.23736\/S0392-0488.19.06301-6"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12432"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555924447"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2004.00411.x"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-72451-5_48-1"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/08923973.2021.1889583"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12846"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13672"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.02037.x"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2012.02863.x"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2021.03.028"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12241"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12935"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12676"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13457"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2008.01419.x"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14130","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cod.14130","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14130","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T10:31:55Z","timestamp":1700476315000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.14130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,28]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/cod.14130"],"URL":"https:\/\/doi.org\/10.1111\/cod.14130","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,28]]},"assertion":[{"value":"2022-02-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}