{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T02:51:39Z","timestamp":1774752699087,"version":"3.50.1"},"reference-count":51,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T00:00:00Z","timestamp":1680566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Semipermeable membranes might be suitable for glove liners or comfort gloves in individuals with irritant contact dermatitis (ICD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the effects of different glove materials on inflammation and epidermal barrier impairment after experimental skin irritation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Nine test areas on the volar forearms of 24 healthy volunteers were irritated with sodium lauryl sulfate (1%) and afterward covered for 6\u2009days (6 or 8\u2009h\/day) with semipermeable Sympatex (SYM), vinyl (OCC), combinations of vinyl with Sympatex (SYM\/OCC) or cotton (COT\/OCC), or left uncovered (CON). Up to day 10, measurements of transepidermal water loss (TEWL), erythema (<jats:italic>a<\/jats:italic>*), skin humidity (SH) and visual scoring (VS) were applied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant differences in skin parameters were found between COT\/OCC and SYM\/OCC as well as between each of the combinations and CON. SYM, COT\/OCC and SYM\/OCC led to better results for most skin parameters than OCC alone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Occlusive material has a negative impact on skin barrier recovery and inflammation after skin irritation whereas SYM is not inferior to uncovered areas indicating good tolerability. Altogether, the data suggest that SYM is a useful alternative to COT as material for glove liners and comfort gloves in ICD patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.14317","type":"journal-article","created":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T22:23:42Z","timestamp":1680647022000},"page":"26-36","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effects of impermeable and semipermeable glove materials on resolution of inflammation and epidermal barrier impairment after experimental skin irritation"],"prefix":"10.1111","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6059-7676","authenticated-orcid":false,"given":"Theres","family":"Heichel","sequence":"first","affiliation":[{"name":"Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm) at the University of Osnabr\u00fcck  Osnabr\u00fcck 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