{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:46:27Z","timestamp":1777391187428,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T00:00:00Z","timestamp":1681084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In 2008, numerous cases of allergic contact dermatitis caused by leather chairs (sofa dermatitis) were reported, with dimethylfumarate being the culprit allergen. However, octylisothiazolinone, methylisothiazolinone and cobalt have also been associated with cases of sofa dermatitis. An antifungal agent, 2\u2010(thiocyanomethylthio)benzothiazole (TCMTB), has also previously been described as a contact allergen in leather.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Seven patients were referred to the Department of Dermatology of the Cliniques universitaires Saint\u2010Luc, Brussels, Belgium with suspicion of allergic contact dermatitis caused by leather sofas. They were patch tested with the European Baseline Series, additional series (according to the patients' history and clinical aspect of the eruption), dimethylfumarate (4\/7 patients) and with TCMTB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All seven patients presented a positive reaction to TCMTB and only one presented a concomitant positive reaction to dimethylfumarate. All patients showed clinical improvement after avoiding contact with their leather sofa.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>2\u2010(Thiocyanomethylthio)benzothiazole (TCMTB) is probably an underestimated allergen present in leather chairs (responsible for the so\u2010called \u2018sofa dermatitis\u2019), and more generally in leather objects. It is, therefore, important to test with TCMTB 0.1% petrolatum in case of contact dermatitis related with leather products.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.14320","type":"journal-article","created":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T22:28:10Z","timestamp":1681165690000},"page":"20-25","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Sofa dermatitis: Value of patch test with 2\u2010(thiocyanomethylthio)benzothiazole"],"prefix":"10.1111","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7000-1672","authenticated-orcid":false,"given":"Anne","family":"Herman","sequence":"first","affiliation":[{"name":"Department of Dermatology Cliniques Universitaires Saint\u2010Luc, Universit\u00e9 Catholique de Louvain (UCLouvain)  Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liliane","family":"Marot","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cliniques Universitaires Saint\u2010Luc, Universit\u00e9 Catholique de Louvain (UCLouvain)  Brussels Belgium"},{"name":"Department of Anatomopathology Cliniques Universitaires Saint\u2010Luc, Universit\u00e9 Catholique de Louvain (UCLouvain)  Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0499-7939","authenticated-orcid":false,"given":"Marie","family":"Baeck","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cliniques Universitaires Saint\u2010Luc, Universit\u00e9 Catholique de Louvain (UCLouvain)  Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2011.00002"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2005.00692.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13295"},{"key":"e_1_2_11_5_1","first-page":"341","article-title":"Determination of TCMTB and other funcigides in leather","volume":"106","author":"Font J","year":"2011","journal-title":"J Am Leather Chem Assoc"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12432"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08622.x"},{"key":"e_1_2_11_8_1","unstructured":"Commission Regulation (EU) No 412\/2012 adopted on May 15 2012. Amending Annex XVII to Regulation (EC) No 1907\/2006 of the European Parliament and of the Council on the Registration Evaluation Authorisation and Restriction of Chemicals (REACH). Official Journal of the European Union. Accessed January 17 2023.https:\/\/eur\u2010lex.europa.eu\/LexUriServ\/LexUriServ.do?uri=OJ:L:2012:128:0001:0003:en:PDF"},{"issue":"11","key":"e_1_2_11_9_1","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1111\/j.1610-0387.2010.07386.x","article-title":"Sofa dermatitis","volume":"8","author":"Schad K","year":"2010","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_11_10_1","unstructured":"European Chemicals Agency (ECHA).Information on Chemicals (benzothiazol\u20102\u2010ylthio)methyl thiocyanate (TCMTB). Accessed January 17 2023.https:\/\/echa.europa.eu\/information-on-chemicals\/biocidal-active-substances\/-\/disas\/substance\/100.040.390"},{"key":"e_1_2_11_11_1","first-page":"22","article-title":"2\u2010(thiocyanomethylthio)\u2010benzothiazole fungicide on leather: a review","volume":"82","author":"Muthusubramanian L","year":"1998","journal-title":"J Soc Leath Technol Chem"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12253"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13810"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13380"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12793"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12670"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13024"},{"key":"e_1_2_11_18_1","unstructured":"European Chemicals Agency (ECHA).Commitee for Risk Assessment (RAC) Committee for Socio\u2010economic Analysis (SEAC).Opinion on an Annex XV Dossier Proposing Restrictions on Skin Sensitising Substances; September 17 2020. Accessed January 20 2023.https:\/\/echa.europa.eu\/documents\/10162\/16dbaec6-4563-6820-ec3d-c0f2124ce725"},{"key":"e_1_2_11_19_1","unstructured":"European Chemicals Agency (ECHA).Annex VI of regulation (EC) No 1272\/2008 (CLP Regulation) (benzothiazol\u20102\u2010ylthio)methyl thiocyanate TCMTB. Accessed January 17 2023.https:\/\/echa.europa.eu\/information\u2010on\u2010chemicals\/cl\u2010inventory\u2010database\/\u2010\/discli\/details\/53225"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002040050315"},{"key":"e_1_2_11_21_1","unstructured":"Unites States Environmental Protection Agency (EPA).Method 637: The Determination of MBTS and TCMTB in Municipal and Industrial Wastewaters; August 1993. Accessed January 17 2023.www.epa.govhttps:\/\/www.epa.gov\/sites\/default\/files\/2015-10\/documents\/method_637_1993.pdf"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14320","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T04:08:13Z","timestamp":1692504493000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.14320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,10]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1111\/cod.14320"],"URL":"https:\/\/doi.org\/10.1111\/cod.14320","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,10]]},"assertion":[{"value":"2022-12-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}