{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:54:38Z","timestamp":1747184078881,"version":"3.40.5"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:00:00Z","timestamp":1695686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2022NSFSC0788"],"award-info":[{"award-number":["2022NSFSC0788"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Furazolidone is a nitrofuran antimicrobial agent used in the treatment of bacterial and protozoal infections. Hypersensitivity to furazolidone is rarely reported and only eight cases have been documented in English since 1967.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To report a 24\u2010year\u2010old man who developed exanthematous drug eruptions in general and swelling sensation of the hands after first dose of oral administration of medicines for <jats:italic>Helicobacter pylori<\/jats:italic> infection 7\u2009h later, who was finally confirmed with delayed\u2010type IV allergic reaction to furazolidone by provocation tests. And to review the existing literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thorough clinical examination, prick, intradermal, and patch tests, drug provocation tests were performed in the patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Skin tests of all used drugs were negative. Drug provocation tests to furazolidone resulted to be positive.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Clinicians should be aware that furazolidone may induce delayed\u2010type allergic reactions; diagnostic approaches should be taken to identify the responsible drug when multiple medications were used concurrently.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.14424","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T09:54:44Z","timestamp":1695722084000},"page":"496-500","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Delayed\u2010type allergic reaction to furazolidone: A case report and review of the literature"],"prefix":"10.1111","volume":"89","author":[{"given":"Feng","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head &amp; Neck Surgery\/Allergy Center of West China Hospital Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongting","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head &amp; Neck Surgery\/Allergy Center of West China Hospital Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head &amp; Neck Surgery\/Allergy Center of West China Hospital Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5674-4485","authenticated-orcid":false,"given":"Juan","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head &amp; Neck Surgery\/Allergy Center of West China Hospital Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9,26]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2016-312288"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e31820fb8f6"},{"issue":"5","key":"e_1_2_12_4_1","first-page":"823","article-title":"Acute pulmonary hypersensitivity to furazolidone","volume":"105","author":"Cortez LM","year":"1972","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1E080"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.49.573.518"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1990.tb01567.x"},{"issue":"4","key":"e_1_2_12_8_1","first-page":"406","article-title":"Vaginal medications as a cause for varied widespread dermatitides","volume":"26","author":"Goette DK","year":"1980","journal-title":"Cutis"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2005.00593.x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/0253-7613.121380"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1978.27.762"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-037375"},{"issue":"3","key":"e_1_2_12_13_1","first-page":"60","article-title":"Nitrofuran\u2010containing chicken feed as an occupational eczematogen","volume":"153","author":"Scharfenberg B","year":"1967","journal-title":"Dermatol Wochenschr"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.10.030"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-022-08924-2"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12842"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2001.450601.x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12269"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14424","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T02:27:54Z","timestamp":1699324074000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.14424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,26]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1111\/cod.14424"],"URL":"https:\/\/doi.org\/10.1111\/cod.14424","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"type":"print","value":"0105-1873"},{"type":"electronic","value":"1600-0536"}],"subject":[],"published":{"date-parts":[[2023,9,26]]},"assertion":[{"value":"2023-06-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}