{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T23:19:54Z","timestamp":1768778394419,"version":"3.49.0"},"reference-count":66,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:00:00Z","timestamp":1700611200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The international classification of diseases, 10th revision (ICD\u201010) includes several unvalidated diagnostic codes for hand eczema (HE). Knowledge is sparse on HE patient characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To validate selected HE ICD\u201010 codes in the Danish National Patient Registry (DNPR) and describe disease characteristics, lifestyle factors and medication use in adult HE patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Nineteen HE ICD\u201010 codes were selected and validated based on patient charts. Five cohorts were constructed based on the diagnostic code, DL30.8H (HE unspecified), in the DNPR: (i) patients with DL30.8H code (<jats:italic>n<\/jats:italic>\u2009=\u20098386), (ii) patients with DL30.8H code, but without atopic dermatitis (AD) (<jats:italic>n<\/jats:italic>\u2009=\u20097406), (iii) sex\u2010 and age\u2010matched general population (<jats:italic>n<\/jats:italic>\u2009=\u20098386) without HE. Two additional cohorts nested in the DNPR included participants from the Danish Skin Cohort, (iv) patients with DL30.8H code but without AD (<jats:italic>n<\/jats:italic>\u2009=\u20091340) and (v) general population cohort (<jats:italic>n<\/jats:italic>\u2009=\u20099876).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>ICD\u201010 codes revealed positive predictive values \u226590% except irritant contact dermatitis (unspecified) (79.7%) and hyperkeratotic hand and foot eczema (84.1%). HE patients were most often women, middle\u2010aged or older, of Danish ethnicity, had an atopic medical history and were smokers. Topical corticosteroid prescriptions were almost doubled in HE cohorts compared to general populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We validated several HE ICD\u201010 codes and identified important HE patient characteristics.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.14456","type":"journal-article","created":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T23:59:34Z","timestamp":1700783974000},"page":"350-364","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Demographics, characteristics and medical treatment among adults with hand eczema in Denmark. A cross\u2010sectional validation and registry\u2010based study"],"prefix":"10.1111","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7177-1054","authenticated-orcid":false,"given":"Maria Oberl\u00e4nder","family":"Christensen","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1289-1827","authenticated-orcid":false,"given":"Yasemin Topal","family":"Y\u00fcksel","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3192-6135","authenticated-orcid":false,"given":"Ida","family":"Vittrup","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7202-0607","authenticated-orcid":false,"given":"Lea Krog","family":"Nymand","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3984-023X","authenticated-orcid":false,"given":"David","family":"Thein","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3702-1409","authenticated-orcid":false,"given":"Line Brok","family":"N\u00f8rreslet","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9301-664X","authenticated-orcid":false,"given":"Jakob Maarbjerg","family":"Toft\u2010Hansen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9343-3960","authenticated-orcid":false,"given":"Anne Klose","family":"Janstrup","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Bispebjerg and Frederiksberg Hospital University of Copenhagen  Copenhagen 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