{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T01:46:03Z","timestamp":1793238363873,"version":"4.5.0"},"reference-count":52,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,1,7]],"date-time":"2024-01-07T00:00:00Z","timestamp":1704585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Healthcare workers (HCWs) are considered a high\u2010risk group for developing hand eczema (HE), mainly owing to wet work and contact with allergens at work. To meta\u2010analyse the prevalence and incidence of HE in HCWs, as well as mapping the prevalence of atopic dermatitis (AD) and HE severity in HCWs. A systematic review and meta\u2010analysis was performed following the Preferred Reporting Items for Systematic Reviews and Meta\u2010analyses 2020 guidelines. Published literature from 2000 to 2022 was eligible based on predefined inclusion and exclusion criteria. A total of 18 studies were included. Pooled life\u2010time, 1\u2010year and point prevalence of self\u2010reported HE in HCWs was 33.4% (95% confidence interval [CI]: 28.3\u201338.6), 27.4% (95% CI: 19.3\u201336.5) and 13.5% (95% CI: 9.3\u201318.4), respectively. AD prevalence was 15.4% (95% CI: 11.3\u201319.9). Overall, the majority of HCWs reported mild HE. One included study assessed HE incidence reporting 34 cases\/1000 person years. Most studies scored low\u2010moderate using the New Ottawa Scale and the pooled point prevalence data showed broad CIs. In conclusion, the high prevalence of HE in HCWs underlines the increased risk and need for preventive measures for this professional group. There is, however, a need of further standardized high\u2010quality studies.<\/jats:p>","DOI":"10.1111\/cod.14489","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T02:35:01Z","timestamp":1704681301000},"page":"331-342","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Prevalence and incidence of hand eczema in healthcare workers: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1289-1827","authenticated-orcid":false,"given":"Yasemin T.","family":"Y\u00fcksel","sequence":"first","affiliation":[{"name":"Department of Dermatology, Bispebjerg and Frederiksberg Hospital University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4090-6726","authenticated-orcid":false,"given":"Cara","family":"Symanzik","sequence":"additional","affiliation":[{"name":"Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm) at Osnabr\u00fcck University Osnabr\u00fcck Germany"},{"name":"Department of Dermatology, Environmental Medicine and Health Theory Osnabr\u00fcck University Osnabr\u00fcck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7177-1054","authenticated-orcid":false,"given":"Maria O.","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Bispebjerg and Frederiksberg Hospital University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3938-7121","authenticated-orcid":false,"given":"Caroline M.","family":"Olesen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Bispebjerg and Frederiksberg Hospital University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3770-1743","authenticated-orcid":false,"given":"Jacob P.","family":"Thyssen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Bispebjerg and Frederiksberg Hospital University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5670-8396","authenticated-orcid":false,"given":"Christoph","family":"Skudlik","sequence":"additional","affiliation":[{"name":"Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm) at Osnabr\u00fcck University Osnabr\u00fcck Germany"},{"name":"Department of Dermatology, Environmental Medicine and Health Theory Osnabr\u00fcck University Osnabr\u00fcck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5406-9458","authenticated-orcid":false,"given":"Swen M.","family":"John","sequence":"additional","affiliation":[{"name":"Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm) at Osnabr\u00fcck University Osnabr\u00fcck Germany"},{"name":"Department of Dermatology, Environmental Medicine and Health Theory Osnabr\u00fcck University Osnabr\u00fcck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7543-8299","authenticated-orcid":false,"given":"Tove","family":"Agner","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Bispebjerg and Frederiksberg Hospital University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1245-024X","authenticated-orcid":false,"given":"Richard","family":"Brans","sequence":"additional","affiliation":[{"name":"Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm) at Osnabr\u00fcck University Osnabr\u00fcck Germany"},{"name":"Department of Dermatology, Environmental Medicine and Health Theory Osnabr\u00fcck University Osnabr\u00fcck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13804"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12134"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14319"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12869"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2008.01362.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-019-01435-2"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.21679"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2016-103632"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16147"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-062194"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70065-7"},{"key":"e_1_2_9_14_1","unstructured":"WellsG SheaB O'ConnellD.The Newcastle\u2010Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta\u2010Analyses.http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2007.06024"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2008.01496.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.01961.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2012.02105.x"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12036"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15813"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12825"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13214"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13009"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13618"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13632"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2021.4046"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000688"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-3904"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13990"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14206"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14006"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdin.2022.02.009"},{"key":"e_1_2_9_33_1","doi-asserted-by":"crossref","unstructured":"SusitaivalP FlyvholmMA MedingB et al.Nordic Occupational Skin Questionnaire (NOSQ\u20102002): a new tool for surveying occupational skin diseases and exposure.2003;49:70\u201076.","DOI":"10.1111\/j.0105-1873.2003.00159.x"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07565.x"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12131"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12275"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12330"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13915"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2000.043002065.x"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14133"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.03.014"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14183"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2001.045002099.x"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2521"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-20-7652"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.2340\/actadv.v102.360"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14048"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12934"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12139"},{"key":"e_1_2_9_50_1","volume-title":"Your Job, Your Choice, Your Oppurtunities. If You Have Asthma. If You Have Hay Fever. If You Have Eczema","author":"Sherson D","year":"2011"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1975.tb05303.x"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2018.10.029"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13212"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T11:36:20Z","timestamp":1730979380000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.14489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,7]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1111\/cod.14489"],"URL":"https:\/\/doi.org\/10.1111\/cod.14489","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,7]]},"assertion":[{"value":"2023-07-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}