{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T08:18:01Z","timestamp":1788250681352,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T00:00:00Z","timestamp":1703635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The relationship between atopic dermatitis (AD) and allergic contact dermatitis (ACD) is a matter of debate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      The purpose of our study is to assess the frequency of\n                      <jats:styled-content style=\"fixed-case\">ACD<\/jats:styled-content>\n                      in patients with\n                      <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                      , the incriminated allergens and the potential risk factors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a prospective study, including cases of AD diagnosed based on Hanifin and Rajka's criteria. All patients were patch tested to the European baseline series and corticosteroid series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ninety\u2010three patients were included. Fifty\u2010six patients (60.2%) had positive patch test results of which 71.4% were relevant. The most frequent allergens were: textile dye mix (24.7%), nickel (20.4%), cobalt (12.9%), isothiazolinone (8.6%), quanterium 15 (4.3%) and balsam of Peru (4.3%). Chromium, fragrance mix I, fragrance mix\n                      <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">PTBP<\/jats:styled-content>\n                      were positive in three cases (3.2%). Two cases of allergy to corticoids were identified. Facial involvement and duration of\n                      <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                      were significantly associated with contact sensitization (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005, respectively). Avoidance of relevant allergens resulted in a statistically significant decrease in\n                      <jats:styled-content style=\"fixed-case\">SCORAD<\/jats:styled-content>\n                      (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ACD remains an important co\u2010morbidity of AD. We observed a high frequency of ACD to textile dyes, isothiazolinones and fragrances. Avoidance of relevant allergens has resulted in an improvement of patients' skin symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cod.14494","type":"journal-article","created":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T02:24:30Z","timestamp":1703730270000},"page":"514-519","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Contact allergy in atopic dermatitis: A prospective study on prevalence, incriminated allergens and clinical insights"],"prefix":"10.1111","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9987-583X","authenticated-orcid":false,"given":"Khaoula","family":"Trimeche","sequence":"first","affiliation":[{"name":"Dermatology Department Fattouma Bourguiba Hospital, University of Monastir  Monastir 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Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monia","family":"Youssef","sequence":"additional","affiliation":[{"name":"Dermatology Department Fattouma Bourguiba Hospital, University of Monastir  Monastir Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jameleddine","family":"Zili","sequence":"additional","affiliation":[{"name":"Dermatology Department Fattouma Bourguiba Hospital, University of Monastir  Monastir Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2017.02.002"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2019.08.012"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14737"},{"issue":"3","key":"e_1_2_10_5_1","first-page":"139","article-title":"Can atopic dermatitis and allergic contact dermatitis 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