{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:19:24Z","timestamp":1791839964447,"version":"4.3.4"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T00:00:00Z","timestamp":1707091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009804","name":"Svenska Diabetesstiftelsen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009804","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010234","name":"Asthma and Allergy Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010234","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022654","name":"HudFonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022654","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Allergic contact dermatitis (ACD) has been reported as an adverse effect from the use of several glucose sensors and insulin pumps from different manufacturers. Isobornyl acrylate (IBOA) has been identified as a major culprit sensitizer, but also other acrylates and (modified) colophonium have been reported as causes of ACD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To report the two first cases diagnosed with ACD caused by the Dexcom G7 (DG7) glucose sensor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>Two children with suspected ACD from DG7 were patch tested with our medical device series with an addition of selected test preparations including two variants of modified colophonium \u2013 methyl hydrogenated rosinate (MHR) and glyceryl hydrogenated rosinate (GHR). Both patients were also tested with acetone extracts made from different parts of the DG7 sensor. The extracts were analysed by gas chromatography\u2013mass spectrometry (GC\u2013MS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both patients tested positive to IBOA, hydroabietyl alcohol and GHR. In addition, patient 1 had a positive reaction to MHR and patient 2 had a positive reaction to colophonium. The GC\u2013MS analyses showed the presence of IBOA and colophonium\u2010related substances in the DG7 extracts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Both patients were diagnosed with contact allergy to well\u2010known medical device\u2010related sensitizers. The presence of IBOA and (modified) colophonium in a newly introduced (on the Swedish market in 2023) glucose sensor is remarkable and indicates an inadequate toxicological assessment of the materials used in the sensor.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.14514","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T07:27:31Z","timestamp":1707290851000},"page":"495-500","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["New device, \u2018old\u2019 allergens. Allergic contact dermatitis caused by the Dexcom <scp>G7<\/scp> glucose sensor"],"prefix":"10.1111","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6172-9274","authenticated-orcid":false,"given":"Martin","family":"Mowitz","sequence":"first","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University, Sk\u00e5ne University Hospital  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University, Sk\u00e5ne University Hospital  Malm\u00f6 Sweden"},{"name":"Department of Dermatology and Venereology Ryhov County Hospital  J\u00f6nk\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Siemund","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University, Sk\u00e5ne University Hospital  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9802-2459","authenticated-orcid":false,"given":"Josefin","family":"Ulriksdotter","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University, Sk\u00e5ne University Hospital  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4797-0269","authenticated-orcid":false,"given":"Cecilia","family":"Svedman","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University, Sk\u00e5ne University Hospital  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12866"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13374"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13781"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14274"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13706"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12995"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13663"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13664"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14213"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13649"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-45395-3_12"},{"key":"e_1_2_9_13_1","volume-title":"Manual of Contact Dermatitis","author":"Fregert S","year":"1981"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12432"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-40221-5_41-2"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-7158.1988.tb05147.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1990.tb01566.x"},{"issue":"4","key":"e_1_2_9_18_1","first-page":"236","article-title":"Allergic contact dermatitis from hydrocolloid dressings","volume":"8","author":"Sasseville D","year":"1997","journal-title":"Am J Contact Dermat"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13323"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2019.0163"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16981"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13243"},{"key":"e_1_2_9_23_1","unstructured":"SvedmanC UlriksdotterJ SukakulT et al.Late\u2010appearing reactions when investigating allergic contact dermatitis to medical devices a problem underestimated? 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