{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T08:18:12Z","timestamp":1788250692215,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T00:00:00Z","timestamp":1723507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007761","name":"Agencia Espa\u00f1ola de Medicamentos y Productos Sanitarios","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007761","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Atopic dermatitis (AD) and allergic contact dermatitis (ACD) are inflammatory skin conditions whose association is not clearly defined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify differences in ACD profile between patients with and without AD among those referred for patch testing. Additionally, to determine the prevalence of sensitisation to standard Spanish contact allergens in both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analysed two groups (AD and non\u2010AD) within the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy (REIDAC). Contact allergy, clinical relevance and epidemiological data were compared between them.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 5055 patients were included. Among them, 23% (1168) had a history or final diagnosis of AD. At least one positive reaction was seen in 468 (40%) of AD patients and 1864 (48%) of non\u2010AD patients. In both groups, the most common positive reactions were to nickel sulphate, methylchloroisothiazolinone\/methylisothiazolinone and cobalt chloride. Age\u2010adjusted OR for sensitisation to nickel sulphate was 0.72 (95% CI: 0.61\u20130.86), indicating a decreased likelihood of sensitisation in AD patients compared to non\u2010AD individuals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We did not find an increased presence of ACD in patients with AD referred for patch testing, exhibiting similar profiles to non\u2010AD population, except for a negative relationship between AD and sensitisation to nickel sulphate.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.14672","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T05:44:07Z","timestamp":1723614247000},"page":"404-411","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Allergic contact dermatitis in adults with and without atopic dermatitis: Evaluation of the Spanish Contact Dermatitis Registry (<scp>REIDAC<\/scp>)"],"prefix":"10.1111","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5153-4262","authenticated-orcid":false,"given":"P.","family":"Chicharro","sequence":"first","affiliation":[{"name":"Hospital Universitario de La Princesa  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Munera\u2010Campos","sequence":"additional","affiliation":[{"name":"Hospital Universitario Germans Trias i Pujol  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Zaragoza\u2010Ninet","sequence":"additional","affiliation":[{"name":"Hospital General Universitario de Valencia  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5434-7753","authenticated-orcid":false,"given":"A.","family":"Gim\u00e9nez\u2010Arnau","sequence":"additional","affiliation":[{"name":"Hospital del Mar Research Institute  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Gonz\u00e1lez\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Hospital Universitario de Araba  Vitoria\u2010Gasteiz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. J.","family":"Miquel\u2010Miquel","sequence":"additional","affiliation":[{"name":"Hospital Arnau de Vilanova  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"C\u00f3rdoba\u2010Guijarro","sequence":"additional","affiliation":[{"name":"Hospital Universitario de Fuenlabrada  Fuenlabrada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5796-7680","authenticated-orcid":false,"given":"T.","family":"Sanz\u2010S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Hospital Universitario Infanta Sof\u00eda  San Sebasti\u00e1n de los Reyes Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Ruiz\u2010Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Complejo Asistencial Universitario de Le\u00f3n  Le\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8532-6338","authenticated-orcid":false,"given":"J. F.","family":"Silvestre\u2010Salvador","sequence":"additional","affiliation":[{"name":"Hospital General de Alicante  Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Serra\u2010Baldrich","sequence":"additional","affiliation":[{"name":"Hospital de La Santa Creu i San Pau  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0199-2756","authenticated-orcid":false,"given":"L.","family":"Borrego","sequence":"additional","affiliation":[{"name":"Complejo Hospitalario Universitario Insular Materno Infantil, Universidad de Las Palmas de Gran Canaria  Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8382-5419","authenticated-orcid":false,"given":"M. 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J.","family":"Ortiz de Frutos","sequence":"additional","affiliation":[{"name":"Hospital Universitario 12 de Octubre  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8309-9725","authenticated-orcid":false,"given":"P.","family":"Mercader\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Hospital General Universitario Morales Meseguer  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Heras\u2010Mendaza","sequence":"additional","affiliation":[{"name":"Hospital Fundaci\u00f3n Jim\u00e9nez D\u00edaz  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Fern\u00e1ndez\u2010Redondo","sequence":"additional","affiliation":[{"name":"Complejo Hospitalario Universitario Santiago de Compostela  Santiago Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Rodr\u00edguez\u2010Serna","sequence":"additional","affiliation":[{"name":"Hospital Universitario La Fe  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Hervella\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Complejo Hospitalario de Navarra  Pamplona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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