{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:13:06Z","timestamp":1782846786337,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T00:00:00Z","timestamp":1724630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Acrylate polymers and cross\u2010polymers (ACPs) are frequently used cosmetic ingredients. The British Society for Cutaneous Allergy (BSCA) and the UK Cosmetic, Toiletry and Perfumery Association (CTPA) collaborated to investigate the allergenic potential of three commonly\u2010used ACPs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective of this study is to determine the prevalence of allergic contact dermatitis (ACD) to three ACPs: glyceryl acrylate\/acrylic acid co\u2010polymer, sodium polyacrylate, and acrylates\/C10\u201030 alkyl acrylate cross\u2010polymer (Carbopol\u00ae).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The BSCA prospectively audited data collected from 20 centres in the UK and Ireland between 1st September 2021 and 1st September 2022. Patients with suspected ACD to (meth)acrylates, with facial dermatitis, or consecutive patients, were patch tested to glyceryl acrylate\/acrylic acid co\u2010polymer 10% aqueous (aq.) sodium polyacrylate 2% aq., and to acrylates\/C10\u201030 alkyl acrylate cross\u2010polymer 2% aq. (Carbopol\u00ae). The frequencies of positive, irritant, and doubtful reactions were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 1302 patients were patch tested. To glyceryl acrylate\/acrylic acid co\u2010polymer, there was one doubtful reaction in a patient allergic to multiple (meth)acrylates, and one irritant. To sodium polyacrylate, there were four irritant reactions, one doubtful, and one positive reaction; in all cases, relevance was unknown and there was no demonstrable (meth)acrylate allergy. There were no reactions to Carbopol\u00ae.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Sensitisation to these concentrations of the three tested ACPs is rare. Elicitation of dermatitis in (meth)acrylate\u2010sensitised patients by exposure to these three ACPs appears unlikely.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.14679","type":"journal-article","created":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T03:59:27Z","timestamp":1724731167000},"page":"491-496","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Sensitisation to the acrylate co\u2010polymers glyceryl acrylate\/acrylic acid co\u2010polymer, sodium polyacrylate and acrylates\/<scp>C10<\/scp>\u201030 alkyl acrylate cross\u2010polymer (Carbopol\u00ae) is rare"],"prefix":"10.1111","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9367-9128","authenticated-orcid":false,"given":"Livia F.","family":"Soriano","sequence":"first","affiliation":[{"name":"University Hospital Southampton NHS Trust  Southampton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5818-3220","authenticated-orcid":false,"given":"M. M. U.","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"University Hospital of Wales  Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippa","family":"Cousen","sequence":"additional","affiliation":[{"name":"South Tees Hospital NHS Foundation Trust  Middlesbrough UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Dawe","sequence":"additional","affiliation":[{"name":"West Herts NHS Trust  Harpenden UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharizan A.","family":"Ghaffar","sequence":"additional","affiliation":[{"name":"Ninewells Hospital and Medical School  Dundee UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Haworth","sequence":"additional","affiliation":[{"name":"St Mary's Hospital  Portsmouth UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0137-5245","authenticated-orcid":false,"given":"Catherine R.","family":"Holden","sequence":"additional","affiliation":[{"name":"Sheffield Teaching Hospitals Foundation Trust  Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3529-1656","authenticated-orcid":false,"given":"Aoife","family":"Hollywood","sequence":"additional","affiliation":[{"name":"South Infirmary Victoria University Hospital  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7494-0765","authenticated-orcid":false,"given":"Graham A.","family":"Johnston","sequence":"additional","affiliation":[{"name":"University Hospitals of Leicester NHS Trust  Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Kirk","sequence":"additional","affiliation":[{"name":"SK\u2010CRS Ltd 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Birmingham Hospitals NHS Trust  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1797-9193","authenticated-orcid":false,"given":"Sarah","family":"Wakelin","sequence":"additional","affiliation":[{"name":"OneWelbeck Skin Health and Allergy  London UK"},{"name":"Imperial College Healthcare NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3876-7237","authenticated-orcid":false,"given":"Heather","family":"Whitehouse","sequence":"additional","affiliation":[{"name":"Leeds teaching Hospitals NHS Trust  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catriona","family":"Wootton","sequence":"additional","affiliation":[{"name":"Oxford University Hospitals NHS Trust  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deirdre A.","family":"Buckley","sequence":"additional","affiliation":[{"name":"Sulis Hospital  Bath 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Cosmetic Ingredient Review.https:\/\/online.personalcarecouncil.org\/ctfa\u2010static\/online\/lists\/cir\u2010pdfs\/FR833.pdfAccessed January 11 2024."},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14441"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01237.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14430"},{"issue":"3","key":"e_1_2_8_18_1","first-page":"e40","article-title":"Two\u2010stage revision Total knee arthroplasty for suspected periprosthetic joint infection and metal and bone cement hypersensitivity","volume":"26","author":"Zmerly H","year":"2019","journal-title":"J Popul Ther Clin Pharmacol"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/NOR.0000000000000162"},{"issue":"4","key":"e_1_2_8_20_1","first-page":"792","article-title":"Contact allergy to acrylate\u2010based dental materials in users and in dental professionals","volume":"4","author":"Jovanovi\u0107 M","year":"2010","journal-title":"HealthMED"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2001.044003153.x"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12995"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13744"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000259"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.07.059"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10253.x"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14679","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T05:25:13Z","timestamp":1744349113000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.14679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,26]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1111\/cod.14679"],"URL":"https:\/\/doi.org\/10.1111\/cod.14679","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,26]]},"assertion":[{"value":"2024-03-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}