{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T01:46:03Z","timestamp":1793238363044,"version":"4.5.0"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:00:00Z","timestamp":1726099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:00:00Z","timestamp":1726099200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Measurements of transepidermal water loss (TEWL) and\n                      <jats:italic>stratum corneum<\/jats:italic>\n                      (SC) pH can help indicate work\u2010related skin barrier damage, but sensitivity to confounding personal and ambient factors limits their potential as biomonitoring tools.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the difference between hand and forearm skin barrier conditions as a tool for early recognition of workers with occupational contact dermatitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants and Methods<\/jats:title>\n                    <jats:p>\n                      The participants were nursing apprentices (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u2009238, median age 19\u2009years) from Zagreb, Croatia. They filled out a questionnaire based on the Nordic Occupational Skin Questionnaire, underwent a clinical examination of skin on the hands, and were evaluated for their TEWL and SC pH on the dorsum of the hand and volar part of the forearm.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We found that the difference between hand and forearm TEWL values (\u0394TEWL) greater than 7\u2009g\/m\n                      <jats:sup>2<\/jats:sup>\n                      \/h, or &gt;50%, or the difference in SC \u0394pH &gt;0.50, predicted visible skin changes found on clinical examination. However, only the association with \u0394pH &gt;0.50 retained statistical significance when controlled for sex, age, ambient temperature, and relative humidity in a multiple regression model.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The difference between hand and forearm SC pH values is suggested as a reliable biomonitoring tool in recognition of damaged skin barrier conditions in occupational settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cod.14690","type":"journal-article","created":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T01:40:08Z","timestamp":1726191608000},"page":"41-50","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Biomonitoring of hand and forearm transepidermal water loss and skin pH among nursing 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