{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:50:31Z","timestamp":1791809431098,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,10,5]],"date-time":"2024-10-05T00:00:00Z","timestamp":1728086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006286","name":"Kongelig Hofbuntmager Aage Bangs Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006286","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Rubber gloves contain rubber accelerators that may cause contact allergy. The content of sensitising rubber accelerators in contemporary rubber gloves is not well known.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Identify and quantify the content of rubber accelerators in disposable rubber gloves.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010one gloves of 49 different brands were collected. Forty\u2010eight of the gloves were disposable and three re\u2010usable. The gloves were analysed for their content of sensitising rubber accelerators, that is, zinc dithiocarbamates, thiurams, thiazoles\/benzothiazoles, diphenylguanidine, and thioureas by high\u2010performance liquid chromatography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Rubber accelerators were identified in 43\/48 (90%) of the disposable gloves. In total, 39 gloves contained zinc dibutyldithiocarbamate (ZDBC) (0.18\u20131.96\u2009mg\/g), 34 zinc diethyldithiocarbamate (ZDEC) (0.032\u20132.78\u2009mg\/g), three zinc dibenzyldithiocarbamate (0.65\u20131.4\u2009mg\/g), one zinc dimethyldithiocarbamate (0.23\u2009mg\/g), and one 1,3\u2010diphenylguanidine (0.21\u2009mg\/g). 2\u2010cyanoethyl dimethyldithiocarbamate (CEDMC) was identified in three gloves (&lt;0.052\u2009mg\/g). The one glove labelled as accelerator free contained ZDBC (1.07\u2009mg\/g). Only few glove packages had the specific content of rubber accelerators labelled.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The most frequent rubber accelerators in rubber gloves are ZDEC and ZDBC. Accelerator\u2010free gloves may contain rubber accelerators. Full labelling of rubber gloves is needed and producers should be sure not to falsely claim that the rubber gloves are free of rubber accelerators.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.14709","type":"journal-article","created":{"date-parts":[[2024,10,5]],"date-time":"2024-10-05T10:00:16Z","timestamp":1728122416000},"page":"131-136","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Contents of sensitising rubber accelerators in disposable rubber gloves: <scp>A Copenhagen<\/scp> market survey"],"prefix":"10.1111","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2989-9198","authenticated-orcid":false,"given":"Christoffer","family":"Kursawe Larsen","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy, National Allergy Research Centre Herlev and Gentofte Hospital  Hellerup Denmark"},{"name":"Faculty of Health Science Institute of Clinical Medicine, University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9756-656X","authenticated-orcid":false,"given":"Jakob F. B.","family":"Schwensen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, National Allergy Research Centre Herlev and Gentofte Hospital  Hellerup Denmark"},{"name":"Faculty of Health Science Institute of Clinical Medicine, University of Copenhagen  Copenhagen Denmark"},{"name":"Department of Dermatology and Allergy Herlev and Gentofte Hospital  Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5506-1319","authenticated-orcid":false,"given":"Claus","family":"Zachariae","sequence":"additional","affiliation":[{"name":"Faculty of Health Science Institute of Clinical Medicine, University of Copenhagen  Copenhagen Denmark"},{"name":"Department of Dermatology and Allergy Herlev and Gentofte Hospital  Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4797-0269","authenticated-orcid":false,"given":"Cecilia","family":"Svedman","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University, Sk\u00e5ne University Hospital  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3537-8463","authenticated-orcid":false,"given":"Jeanne D.","family":"Johansen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, National Allergy Research Centre Herlev and Gentofte Hospital  Hellerup Denmark"},{"name":"Faculty of Health Science Institute of Clinical Medicine, University of Copenhagen  Copenhagen Denmark"},{"name":"Department of Dermatology and Allergy Herlev and Gentofte Hospital  Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ola","family":"Bergendorff","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology Lund University, Sk\u00e5ne University Hospital  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,5]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/COD.14421"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e31827b14e1"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555\u20102202"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/OCCMED\/KQAB118"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u20100536.2011.01937.X"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/COD.12736"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u20100536.2006.00912.X"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/COD.12010"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000342"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u20100536.2012.02139.X"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1034\/J.1600\u20100536.2003.480107.X"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/COD.14553"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/COD.13042"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/JDV.17238"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/COD.14357"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/JDV.13684"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/COD.14321"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/COD.12886"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/COD.12276"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1034\/J.1600\u20100536.2000.043001009.X"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2010.09088"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/TOXSCI\/66.2.226"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u20100536.2007.01194.X"},{"key":"e_1_2_12_25_1","doi-asserted-by":"crossref","unstructured":"Kursawe Larsen C Funch AB Vaher H et al. 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