{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T06:22:10Z","timestamp":1774678930559,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:00:00Z","timestamp":1741132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006286","name":"Kongelig Hofbuntmager Aage Bangs Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006286","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hand eczema (HE) is described as a common disease in Greenland, but studies on its epidemiology and severity are lacking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the point prevalence and severity of HE among adults in East Greenland in relation to age, sex, and occupation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In May 2022, we conducted a cross\u2010sectional study in Tasiilaq, East Greenland. All adults aged \u2265\u200918\u2009years were invited (<jats:italic>n<\/jats:italic> = 1311 individuals).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 295 participants accepted the invitation. Among these, the point prevalence of HE was 22.4% (95% confidence interval [CI]: 18.0\u201327.5, <jats:italic>n<\/jats:italic>\u2009=\u200966\/295), and 5.0% based on the total invited population (<jats:italic>n<\/jats:italic>\u2009=\u200966\/1311). The median age of participants with HE was 40\u2009years (interquartile range [IQR]: 30\u201354), and the median age at disease onset was 25\u2009years ([IQR]: 19\u201340). Females were more frequently affected than males (65.2%, <jats:italic>n<\/jats:italic>\u2009=\u200943\/66). Atopic dermatitis was diagnosed in 7.6% of participants with HE. The mean Hand Eczema Severity Index (HECSI) score was 21 (range 2\u2013112), and exposure to wet work was reported by 57.4% of the participants with HE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Hand eczema is common in East Greenland, with a point prevalence similar to that in Nordic countries. The severity and distribution of HE in relation to age, sex, and occupation were comparable to those reported in other European studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cod.14781","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T17:18:17Z","timestamp":1741713497000},"page":"49-55","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Prevalence and Severity of Hand Eczema Among Adults in Tasiilaq, East Greenland"],"prefix":"10.1111","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5553-3213","authenticated-orcid":false,"given":"Morten Bahrt","family":"Haulrig","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy Herlev and Gentofte Hospital  Hellerup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"},{"name":"Copenhagen Research Group for Inflammatory Skin, Herlev and Gentofte Hospital  Hellerup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna M.","family":"Andersson","sequence":"additional","affiliation":[{"name":"Copenhagen Research Group for Inflammatory Skin, Herlev and Gentofte Hospital  Hellerup Denmark"},{"name":"Department of Dermatology Bispebjerg University Hospital  Copenhagen Denmark"},{"name":"Institute of Health and Nature, Ilisimatusarfik, University of Greenland  Nuussuaq Greenland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9914-1545","authenticated-orcid":false,"given":"Julia\u2010Tatjana","family":"Maul","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital of Z\u00fcrich  Z\u00fcrich Switzerland"},{"name":"Faculty of Medicine University of Z\u00fcrich  Z\u00fcrich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingyuan","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Dermatopharmacology University of Manchester  Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3325-3675","authenticated-orcid":false,"given":"Su M.","family":"Lwin","sequence":"additional","affiliation":[{"name":"St John's Institute of Dermatology, School of Basic and Medical Biosciences, King's College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4884-6286","authenticated-orcid":false,"given":"Carsten","family":"Flohr","sequence":"additional","affiliation":[{"name":"Global Atopic Dermatitis Atlas, St John's Institute of Dermatology, King's College London and Guy's &amp; St Thomas' NHS Foundation Trust  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lone S.","family":"Hove","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Queen Ingrids Hospital  Nuuk Greenland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5371-4427","authenticated-orcid":false,"given":"Christopher E. M.","family":"Griffiths","sequence":"additional","affiliation":[{"name":"St John's Institute of Dermatology, School of Basic and Medical Biosciences, King's College London  London UK"},{"name":"Centre for Dermatology Research University of Manchester  Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Koch","sequence":"additional","affiliation":[{"name":"Institute of Health and Nature, Ilisimatusarfik, University of Greenland  Nuussuaq Greenland"},{"name":"Department of Internal Medicine Queen Ingrids Hospital  Nuuk Greenland"},{"name":"Department of Infectious Disease Epidemiology and Prevention Statens Serum Institut  Copenhagen Denmark"},{"name":"Department of Infectious Diseases Rigshospitalet University Hospital  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5506-1319","authenticated-orcid":false,"given":"Claus","family":"Zachariae","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Herlev and Gentofte Hospital  Hellerup Denmark"},{"name":"Copenhagen Research Group for Inflammatory Skin, Herlev and Gentofte Hospital  Hellerup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob Pontoppidan","family":"Thyssen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bispebjerg University Hospital  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7543-8299","authenticated-orcid":false,"given":"Tove","family":"Agner","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bispebjerg University Hospital  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16061"},{"key":"e_1_2_10_3_1","unstructured":"Statistics Greenland accessed June 14 2024 https:\/\/stat.gl."},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2014.11.012"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.7241\/ourd.20242.19"},{"issue":"2","key":"e_1_2_10_6_1","first-page":"1","article-title":"Work Environment, Occupational Diseases and Accidents Among Seafood Industry Workers in Greenland","volume":"69","author":"Laustsen B. 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