{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:18Z","timestamp":1787014038731,"version":"build-2736575974"},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T00:00:00Z","timestamp":1743552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2025,7]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n In Amsterdam, in 2024, patch testing with Brazilian propolis yielded high rates of positive reactions (>\u200920%), whereas reactivity to Chinese propolis was significantly lower (3.5%). Differences in the composition were suggested as a possible explanation.<\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n 1. To study the composition of 3 propolis samples (2 Chinese and 1 Brazilian) used for preparing commercial test allergens; 2. To study the influence of different enrichment times on the qualitative and quantitative composition of Brazilian propolis.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n Analyses were performed using gas chromatography\u2013mass spectrometry\/flame ionisation detection (GC\u2013MS\/FID) of the volatile components obtained by headspace SPME (solid phase microextraction).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A strong difference between the composition of the Brazilian propolis sample and both samples of Chinese propolis was found. Major ingredients in Brazilian propolis were hydrocinnamic acid (16.9%), (\n E<\/jats:italic>\n )\u2010nerolidol (7.41%), spathulenol (5.45%) and junenol (4.01%). Major ingredients in Chinese propolis were (\n E<\/jats:italic>\n )\u2010cinnamyl alcohol (8.08% and 24.96%), 2\u2010phenethyl alcohol (8.93% and 11.25%), \u03b1\u2010curcumene (8.77% and 8.81%) and guaiol (5.96% and 5.72%).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The volatile fractions of Brazilian propolis and Chinese propolis used for patch testing have very different compositions. Whether this causes or contributes to the differences in patch test reactivity has to be investigated further.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/cod.14796","type":"journal-article","created":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T07:12:46Z","timestamp":1743577966000},"page":"56-60","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Composition of Brazilian and Chinese Propolis for Patch Testing"],"prefix":"10.1111","volume":"93","author":[{"given":"Evelyn","family":"Calta","sequence":"first","affiliation":[{"name":"Kurt Kitzing GmbH Wallerstein Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6666-7292","authenticated-orcid":false,"given":"Anton","family":"de Groot","sequence":"additional","affiliation":[{"name":"Dermato\u2010Allergology and Occupational Dermatology Amsterdam University Medical Centers Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma M.","family":"van Oers","sequence":"additional","affiliation":[{"name":"Amsterdam University Medical Centers Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0679-4131","authenticated-orcid":false,"given":"Norbertus A.","family":"Ipenburg","sequence":"additional","affiliation":[{"name":"Dermato\u2010Allergology and Occupational Dermatology Amsterdam University Medical Centers Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7580-0684","authenticated-orcid":false,"given":"Thomas","family":"Rustemeyer","sequence":"additional","affiliation":[{"name":"Dermato\u2010Allergology and Occupational Dermatology Amsterdam University Medical Centers Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14678"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14748"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14701"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000011"},{"issue":"1","key":"e_1_2_9_6_1","first-page":"53","article-title":"Can Patch Testing With Propolis Be Improved?","volume":"91","author":"Antelmi A.","year":"2024","journal-title":"Contact Dermatitis"},{"key":"e_1_2_9_7_1","volume-title":"Monographs in Contact Allergy, Volume II. Fragrances and Essential Oils","author":"De Groot A. C.","year":"2019"},{"key":"e_1_2_9_8_1","unstructured":"PubMed Search (3\u20102\u20102025) With All Chemical Names in Table\u00a01 in Combination with \u2018Allergy\u2019 \u2018Hypersensitivity\u2019 \u2018Dermatitis\u2019 and \u2018Eczema\u2019."}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14796","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T09:22:28Z","timestamp":1754904148000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.14796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,2]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1111\/cod.14796"],"URL":"https:\/\/doi.org\/10.1111\/cod.14796","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,2]]},"assertion":[{"value":"2025-02-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}