{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T14:21:18Z","timestamp":1790432478882,"version":"4.1.0"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T00:00:00Z","timestamp":1746316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2025,8]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n \n In patch testing, co\u2010reactivity between\n \n Myroxylon pereirae<\/jats:italic>\n <\/jats:styled-content>\n resin, colophonium and propolis is well recognised. One of the possible explanations is that these materials have common allergenic ingredients.\n <\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n To identify the main ingredients in\n \n M. pereirae<\/jats:italic>\n <\/jats:styled-content>\n resin and colophonium samples used in the preparation of commercial patch test allergens and to compare their compositions with each other as well as with propolis.\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n \n Analyses were performed on\n \n M. pereirae<\/jats:italic>\n <\/jats:styled-content>\n resin and colophonium samples using gas chromatography\u2013mass spectrometry\/flame ionisation detection of the volatile components obtained by headspace SPME (solid phase microextraction).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The main ingredients in\n \n M. pereirae<\/jats:italic>\n <\/jats:styled-content>\n resin were benzyl benzoate, (\n E)<\/jats:italic>\n \u2010nerolidol, benzoic acid, benzyl alcohol, (\n E<\/jats:italic>\n )\u2010cinnamic acid, vanillin and (\n E<\/jats:italic>\n )\u2010benzyl cinnamate. In colophonium, longifolene, caryophyllene oxide, acetone\u2009+\u2009formic acid, \u03b1\u2010terpineol and \u03b4\u2010cadinene\u2009+\u2009calamenene were the major constituents.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n The major ingredients of the volatile fractions of\n \n M. pereirae<\/jats:italic>\n <\/jats:styled-content>\n resin and colophonium are quite different; common haptens in volatile ingredients cannot readily explain co\u2010reactivity.\n \n M. pereirae<\/jats:italic>\n <\/jats:styled-content>\n resin has cinnamic acid\u2010 and benzoic acid derivatives in common with propolis and in addition (\n E<\/jats:italic>\n )\u2010nerolidol and vanillin with Brazilian propolis and benzyl alcohol with Chinese propolis. Colophonium shares various ingredients with Brazilian propolis but few with the Chinese variety.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/cod.14807","type":"journal-article","created":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T21:25:03Z","timestamp":1746393903000},"page":"108-113","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Composition of\n Myroxylon pereirae<\/i>\n Resin and Colophonium for Patch Testing"],"prefix":"10.1111","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6666-7292","authenticated-orcid":false,"given":"Anton","family":"de Groot","sequence":"first","affiliation":[{"name":"Dermato\u2010Allergology and Occupational Dermatology Amsterdam University Medical Centers Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn","family":"Calta","sequence":"additional","affiliation":[{"name":"Kurt Kitzing GmbH Wallerstein Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0679-4131","authenticated-orcid":false,"given":"Norbertus A.","family":"Ipenburg","sequence":"additional","affiliation":[{"name":"Dermato\u2010Allergology and Occupational Dermatology Amsterdam University Medical Centers Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma M.","family":"van Oers","sequence":"additional","affiliation":[{"name":"Amsterdam University Medical Centers Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7580-0684","authenticated-orcid":false,"given":"Thomas","family":"Rustemeyer","sequence":"additional","affiliation":[{"name":"Dermato\u2010Allergology and Occupational Dermatology Amsterdam University Medical Centers Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,4]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000011"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13263"},{"key":"e_1_2_9_4_1","volume-title":"Chapter\u00a03.126 Myroxylon pereirae resin (Balsam of Peru), pp. 527\u2013552; Chapter\u00a03.70 Fragrance Mix I, pp. 296\u2013319","author":"De Groot A. C.","year":"2019"},{"key":"e_1_2_9_5_1","volume-title":"Chapter\u00a02.126 Colophonium, pp. 336\u2013355. Chapter\u00a02.385 Propolis, pp. 1042\u20131055","author":"De Groot A. C.","year":"2018"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-68617-2_41"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14796"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14678"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14748"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14701"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14773"}],"container-title":["Contact Dermatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cod.14807","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T08:52:35Z","timestamp":1752828755000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cod.14807"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1111\/cod.14807"],"URL":"https:\/\/doi.org\/10.1111\/cod.14807","archive":["Portico"],"relation":{},"ISSN":["0105-1873","1600-0536"],"issn-type":[{"value":"0105-1873","type":"print"},{"value":"1600-0536","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,4]]},"assertion":[{"value":"2025-03-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}