{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T08:09:48Z","timestamp":1777622988926,"version":"3.51.4"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Atopic dermatitis is a common chronic inflammatory skin condition. Data on contact sensitization in adults with atopic dermatitis remain limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the prevalence of contact sensitization in adults with and without AD:<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients\/Methods<\/jats:title>\n                    <jats:p>A monocentric, retrospective study analysed 8967 adults (\u2265\u200916\u2009years) patch\u2010tested at the University of Padua (1997\u20132018). Patients were tested with a standard baseline series (44 allergens). 540 (6.0%) patients had atopic dermatitis; 8273 (92.3%) did not; 154 (1.7%) had missing\/uncertain AD status and were excluded from subgroup comparisons.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Contact sensitization prevalence was 65.4% in both groups. Adults with atopic dermatitis showed significantly higher rates of sensitization to formaldehyde (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.00001), HICC (hydroxyisohexyl 3\u2010cyclohexene carboxaldehyde) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), thiuram mix (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03), and carba mix (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004). Non\u2010AD patients showed significantly higher sensitization to nickel (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001), disperse blue (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006), and primin (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.05). Nickel was the most frequent allergen (21.30% AD; 27.59% non\u2010AD).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Higher prevalence of contact sensitization to specific allergens in adults with atopic dermatitis suggests a tailored patch test series including allergens from rubber, fragrance, and preservative groups. The lower prevalence of metal sensitization in patients with atopic dermatitis may reflect distinct immunological mechanisms that warrant further research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cod.70086","type":"journal-article","created":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T01:10:23Z","timestamp":1769735423000},"page":"465-474","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Contact Sensitization in Adults With Atopic Dermatitis: A 21\u2010Year Single\u2010Center Tertiary Experience"],"prefix":"10.1111","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3583-0816","authenticated-orcid":false,"given":"Francesca","family":"Caroppo","sequence":"first","affiliation":[{"name":"Dermatology Unit, Department of Medicine (DIMED) University of Padua  Padua Italy"},{"name":"Paediatric Dermatology Regional Center, Department of Women's and Children's Health (SDB) University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Zambello","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medicine (DIMED) University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Biolo","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medicine (DIMED) University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5014-1122","authenticated-orcid":false,"given":"Fortunato","family":"Cassalia","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medicine (DIMED) University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Ventura","sequence":"additional","affiliation":[{"name":"Department of Statistics University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5791-0775","authenticated-orcid":false,"given":"Anna","family":"Belloni Fortina","sequence":"additional","affiliation":[{"name":"Paediatric Dermatology Regional Center, Department of Women's and Children's Health (SDB) University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,29]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12619"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14691"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16364"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12432"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14068"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2021.03.028"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14973"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-017-0340-7"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2017.4898"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13363"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12043"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12148"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14669"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000158"},{"issue":"1","key":"e_1_2_14_16_1","first-page":"323","article-title":"Formaldehyde May Be Found in Cosmetic Products Even When Unlabelled","volume":"10","author":"Malinauskiene L.","year":"2015","journal-title":"Open Med (Wars)"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14089"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12409"},{"issue":"3","key":"e_1_2_14_19_1","first-page":"112","article-title":"Methylchloroisothiazolinone and Methylisothiazolinone: Preservatives Causing Contact Dermatitis","volume":"24","author":"Castanedo\u2010Tardan M. 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