{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T18:16:30Z","timestamp":1783016190281,"version":"3.54.6"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:00:00Z","timestamp":1775174400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:00:00Z","timestamp":1775174400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Allergic contact dermatitis is influenced by demographic factors. Updated epidemiologic data are needed to optimise patch test panels and preventive strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate trends and determinants of allergen sensitization in Korean patients undergoing patch testing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective analysis of patch test records of 2271 patients at 15 university hospitals in Korea between 2019 and 2024. Patch test reactions were interpreted according to International Contact Dermatitis Research Group criteria. Association with age, sex, and body site was assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 57.1% of patients exhibited at least one positive reaction; among patients with positive reactions, 48.7% exhibited multi\u2010sensitizations. Most frequent positive patch reactions were to nickel (29.0%), cobalt (18.2%), and chromium (8.2%). Women were more frequently sensitised to nickel and cobalt. Sensitization to fragrance mix I,\n                      <jats:italic>Myroxylon pereirae<\/jats:italic>\n                      resin, and p\u2010phenylenediamine increased with age, whereas sensitization to thimerosal decreased. Facial involvement was associated with higher sensitization to lanolin alcohol; hand involvement with 2\u2010mercaptobenzothiazole, colophonium, 4\u2010tert\u2010butylphenol formaldehyde resin and thimerosal; and scalp involvement with mercapto mix, 4\u2010tert\u2010butylphenol formaldehyde resin, p\u2010phenylenediamine, and lanolin alcohol.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Metals, particularly nickel and cobalt, remain the predominant sensitizers in Korea. Age, sex, and localization differences underscore the need for targeted screening and public health strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cod.70143","type":"journal-article","created":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T03:34:36Z","timestamp":1775273676000},"page":"182-191","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Trends in Contact Sensitization Among Korean Patients: A Multicenter 6\u2010Year Retrospective Patch Test Study"],"prefix":"10.1111","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0660-8098","authenticated-orcid":false,"given":"Myoung Shin","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Dermatology Inje University Sanggye Paik Hospital, Inje University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5027-6871","authenticated-orcid":false,"given":"Ho Sung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Inje University Sanggye Paik Hospital, Inje University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9924-515X","authenticated-orcid":false,"given":"Eun Joo","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hallym University Sacred Heart Hospital, Hallym University College of Medicine  Anyang South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5846-0008","authenticated-orcid":false,"given":"Hye One","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7519-8192","authenticated-orcid":false,"given":"Jungsoo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Pusan National University Yangsan Hospital  Yangsan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2925-3074","authenticated-orcid":false,"given":"Dong Hun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Seoul National University Hospital, Seoul National University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3432-8306","authenticated-orcid":false,"given":"Joon Min","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center, Ulsan University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4225-0414","authenticated-orcid":false,"given":"Sung Eun","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asan Medical Center, Ulsan University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0995-5711","authenticated-orcid":false,"given":"Hye Jung","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Medical Center  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4240-9675","authenticated-orcid":false,"given":"Joo Yeon","family":"Ko","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hanyang University College of Medicine and Hanyang University Seoul Hospital  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8253-6188","authenticated-orcid":false,"given":"Mihn\u2010Sook","family":"Jue","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hanyang University College of Medicine and Hanyang University Seoul Hospital  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0248-7708","authenticated-orcid":false,"given":"Sun Young","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chung\u2010Ang University Gwangmyeong Hospital, Chung\u2010Ang University College of Medicine  Gwangmyeong South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2456-7573","authenticated-orcid":false,"given":"Jiehyun","family":"Jeon","sequence":"additional","affiliation":[{"name":"Department of Dermatology Korea University Guro Hospital, Korea University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9072-201X","authenticated-orcid":false,"given":"Myung Hwa","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology College of Medicine, Dankook University  Cheonan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8443-724X","authenticated-orcid":false,"given":"Seung Hyun","family":"Cheong","sequence":"additional","affiliation":[{"name":"Department of Dermatology Konyang University Hospital, Konyang University College of Medicine  Daejeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9501-2914","authenticated-orcid":false,"given":"Young\u2010Jun","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kangbuk Samsung Hospital, Sungkyunkwan University School 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