{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T13:53:37Z","timestamp":1791208417987,"version":"4.1.0"},"reference-count":50,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100021201","name":"European Academy of Dermatology and Venereology","doi-asserted-by":"publisher","award":["PPRC\u20102018\u20108"],"award-info":[{"award-number":["PPRC\u20102018\u20108"]}],"id":[{"id":"10.13039\/501100021201","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contact Dermatitis"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Allergens are periodically added to the European Baseline Series (EBS) to audit their value in consecutive patch testing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To present results of audit allergens tested in consecutive patients in 54 departments in 13 European countries during 2021 and 2022.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Anonymized or pseudonymized individual data, and partly aggregated data on patch test rest results and their clinical relevance were prospectively collected and centrally pooled and analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In 2021 and 2022, 18\u2009832 patients were patch tested with the EBS, and 2860 with the TRUE Test baseline series (supplemented with some missing EBS allergens). Of these patients, 17\u2009359 were additionally tested with one or more of the 19 audit allergen preparations examined. Apart from the terpene hydroperoxides (OOH) which yielded the highest numbers of positive patch test reactions (linalool\u2010OOH 1% pet.: 7.65 (7.09%\u20138.23%) [95% CI] and limonene\u2010OOH 0.3% pet. 6.78 (6.26%\u20137.32%)), positive reactions were most often seen to benzisothiazolinone (3.71 (3.3%\u20134.15%)), sodium metabisulfite (3.49 (3.14%\u20133.88%)),\n                      <jats:italic>Evernia furfuracea<\/jats:italic>\n                      (tree moss, 1.79 (1.4%\u20132.26%)), and decyl and lauryl glucoside, at 1.49 (1.25%\u20131.76%) and 1.26 (1.05%\u20131.51%), respectively. The other allergens yielded around 1% or fewer positive patch test reactions. Clinical relevance varied, with\n                      <jats:italic>Evernia furfuracea<\/jats:italic>\n                      , 2\u2010bromo\u20102\u2010nitropropane\u20101,3\u2010diol and terpene hydroperoxides considered relevant in more than 2\/3 cases, while for other frequent sensitizers benzisothiazolinone and sodium metabisulfite, relevance could be confirmed in half of the cases or less often.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The current results, along with other published data, will serve to inform decisions concerning possible revision of the EBS, considering frequency of positive reactions, their clinical relevance and the overall reaction profile of each of the allergens.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cod.70183","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T02:23:21Z","timestamp":1778811801000},"page":"276-285","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Patch Test Results With Additions to the European Baseline Series, 2021\/22\u2014Joint European Results of the\n                    <scp>\n                      ESSCA\n                      <sup>A<\/sup>\n                    <\/scp>\n                    and the\n                    <scp>\n                      EBS\n                      <sup>B<\/sup>\n                    <\/scp>\n                    Working Groups of the\n                    <scp>ESCD<\/scp>\n                    , and the\n                    <scp>\n                      GEIDAC\n                      <sup>C<\/sup>\n                    <\/scp>"],"prefix":"10.1111","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4498-3710","authenticated-orcid":false,"given":"Wolfgang","family":"Uter","sequence":"first","affiliation":[{"name":"Department of Medical Informatics, Biometry and Epidemiology Friedrich\u2010Alexander\u2010Universit\u00e4t Erlangen\u2010N\u00fcrnberg  Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7253-3461","authenticated-orcid":false,"given":"Stephen Mark","family":"Wilkinson","sequence":"additional","affiliation":[{"name":"Dermatology Department Leeds Teaching Hospitals NHS Trust  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4411-3088","authenticated-orcid":false,"given":"Andrea","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Carl Gustav Carus, Technical University  Dresden 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Medical Center G\u00f6ttingen  G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6837-4402","authenticated-orcid":false,"given":"Heinrich","family":"Dickel","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology St. Josef Hospital, University Medical Center, Ruhr University Bochum  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1735-4425","authenticated-orcid":false,"given":"Rosella","family":"Gallo","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Health Sciences University of Genoa and Ospedale Policlinico San Martino, IRCCS  Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5434-7753","authenticated-orcid":false,"given":"Ana Gim\u00e9nez","family":"Arnau","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital del Mar Research Institute Universitat Pompeu Fabra de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6842-1360","authenticated-orcid":false,"given":"Margarida","family":"Gon\u00e7alo","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital, Coimbra Local Health Unit and Faculty of Medicine, University of Coimbra  Coimbra Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7074-2374","authenticated-orcid":false,"given":"Dimitra","family":"Koumaki","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital of Heraklion  Heraklion Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander 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