{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T14:34:41Z","timestamp":1780497281590,"version":"3.54.1"},"reference-count":6,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,3,27]],"date-time":"2013-03-27T00:00:00Z","timestamp":1364342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim\u2002<\/jats:bold> To determine the long\u2010term outcomes of patients in whom no initial cause for their anaemia is established.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> Six hundred and thirty\u2010nine patients presenting to an iron deficiency anaemia pathway were prospectively entered onto a database. Initial assessment included haematological review, coeliac screen, oesophagogastroduodenoscopy and colonic imaging as per British Society of Gastroenterology guidelines. A 5\u2010year audit of outcomes was undertaken using patient medical records and hospital laboratory databases.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> A diagnosis was found initially in 266 (42%) patients, with 124 (19%) having a gastrointestinal (GI) luminal neoplasm, 54 (8%) of which were malignant. Twelve patients had a nonluminal or non\u2010GI malignancy. Eighty\u2010eight (14%) had benign upper GI bleeding and 23 (4%) had coeliac disease. One hundred and forty\u2010three (22%) did not have confirmed iron deficiency anaemia on review of haematinics. Complete records were available for 595 (93%) patients at 5\u2003years. Of the 373 patients in whom a cause was not initially diagnosed, 6 (2%) were ultimately diagnosed with a GI luminal malignancy and 18 (5%) with a nonluminal or non\u2010GI malignancy. There was no difference in the incidence of malignancies between those with or without confirmed iron deficiency.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Most patients in whom no cause was found at initial investigation resolve on oral iron supplements. Patients with normal ferritin values had as high an incidence of GI malignancies as those with low values and should be investigated. In the over 50s if the anaemia remains after a course of iron further investigation is recommended as there is a significant incidence of both GI and non\u2010GI pathology.<\/jats:p>","DOI":"10.1111\/codi.12040","type":"journal-article","created":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T05:40:22Z","timestamp":1349070022000},"page":"423-427","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Attendance at iron deficiency anaemia clinic: audit of outcomes 5\u2003years on"],"prefix":"10.1111","volume":"15","author":[{"given":"S.","family":"Pengelly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Fabricius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"McMenamin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Metzner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. J.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. B.","family":"Hosie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,27]]},"reference":[{"key":"e_1_2_7_2_2","unstructured":"British Society of Gastroenterology.Guidelines for the management of iron deficiency anaemia2005."},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.79.930.226"},{"key":"e_1_2_7_4_2","first-page":"885","article-title":"Long\u2010term follow\u2010up of older patients with iron deficiency anaemia after a negative GI evaluation","volume":"91","author":"Gordon S","year":"1996","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-9999"},{"issue":"4","key":"e_1_2_7_6_2","first-page":"S1","article-title":"Guidelines for the management of iron deficiency anaemia","volume":"46","author":"Goddard AF","year":"2000","journal-title":"Gut"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1053\/crad.2000.0672"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.12040","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.12040","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T20:34:06Z","timestamp":1697661246000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.12040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,27]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1111\/codi.12040"],"URL":"https:\/\/doi.org\/10.1111\/codi.12040","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,27]]},"assertion":[{"value":"2013-03-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}