{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:35:36Z","timestamp":1782848136454,"version":"3.54.5"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,4,25]],"date-time":"2013-04-25T00:00:00Z","timestamp":1366848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Program for Outstanding Medical Academic Leader, Beijing, People's Republic of China"},{"name":"the Program for Outstanding Medical Academic Leader, Beijing, People's Republic of China","award":["no. 2009-1-03"],"award-info":[{"award-number":["no. 2009-1-03"]}]},{"name":"the New Century National Hundred, Thousand, and Ten Thousand Talent Project, Republic of China","award":["nos 09-911-002 and 08-009"],"award-info":[{"award-number":["nos 09-911-002 and 08-009"]}]},{"name":"the Basic and Clinical Cooperation Project of Capital Medical University","award":["10JL04"],"award-info":[{"award-number":["10JL04"]}]},{"name":"the Training Scheme for Excellent Talents, Beijing","award":["2011D003034000003"],"award-info":[{"award-number":["2011D003034000003"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Ligation of the intersphincteric fistula tract and reinforcement with a bioprosthetic graft are two recently reported procedures that have shown promise in the treatment of anal fistula. This study was undertaken to validate combining ligation of the intersphincteric fistula tract plus bioprosthetic anal fistula plug and report our preliminary results and experience.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Twenty\u2010one patients with transsphincteric anal fistula were treated with ligation of the intersphincteric fistula tract plus concurrent bioprosthetic plug of the anal fistula. We evaluated healing time, fistula closure rate and postoperative anal function according to the <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>exner continence score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No mortality or major complications were observed. Median operative time was 20 (range 15\u201340)\u00a0min. After a median follow\u2010up of 14 (range 12\u201315)\u00a0months, the overall success rate was 95% (20\/21), with a median healing time of 2 (range 2\u20133) weeks for external anal fistula opening and 4 (range 3\u20137)\u00a0weeks for intersphincteric groove incision. Only 1 (5%) patient reported rare incontinence for gas postoperatively (<jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>exner score 1).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Ligation of the intersphincteric fistula tract plus a bioprosthetic anal fistula plug is an easy, safe, effective and useful alternative in the management of anal fistula. Further randomized controlled studies are necessary to better evaluate long\u2010term results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12062","type":"journal-article","created":{"date-parts":[[2012,10,16]],"date-time":"2012-10-16T09:38:21Z","timestamp":1350380301000},"page":"582-586","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Ligation of the intersphincteric fistula tract plus a bioprosthetic anal fistula plug (<scp>LIFT<\/scp>\u2010Plug): a new technique for fistula\u2010in\u2010ano"],"prefix":"10.1111","volume":"15","author":[{"given":"J. G.","family":"Han","sequence":"first","affiliation":[{"name":"Department of General Surgery Beijing Chaoyang Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. 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