{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:04:25Z","timestamp":1767164665357,"version":"build-2238731810"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,4,25]],"date-time":"2013-04-25T00:00:00Z","timestamp":1366848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,5]]},"abstract":"Abstract<\/jats:title>\n \n Aim<\/jats:title>\n \n The treatment of solitary rectal ulcer syndrome (\n SRUS<\/jats:styled-content>\n ) is notoriously difficult. Laparoscopic ventral mesh rectopexy (\n LVMR<\/jats:styled-content>\n ) is a nonresectional technique for patients with full thickness external rectal prolapse and internal prolapse with obstructed defaecation syndrome (\n ODS<\/jats:styled-content>\n ), features associated in the pathogenesis of\n SRUS<\/jats:styled-content>\n . Our aim was to assess the short\u2010 and long\u2010term efficacy of\n LVMR<\/jats:styled-content>\n in treating\n SRUS<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Method<\/jats:title>\n \n Forty\u2010eight patients with\n SRUS<\/jats:styled-content>\n who underwent\n LVMR<\/jats:styled-content>\n over a 15\u2010year period (December 1996 to July 2012) were identified from a prospectively maintained electronic database.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Forty\u2010eight patients, 38 (79%) women, median age 43 (18\u201380) years, median body mass index 26 (21\u201340)\u00a0kg\/m\n 2<\/jats:sup>\n underwent\n LVMR<\/jats:styled-content>\n for\n SRUS<\/jats:styled-content>\n after initial biofeedback. The median follow\u2010up was 33\u00a0months (95%\n CI<\/jats:styled-content>\n 31\u201355, range 1\u2013186\u00a0months); 52% were followed for more than 3\u00a0years and 13 (27%) for more than 5\u00a0years. Five (10%) had relapsed following a response to stapled transanal rectal resection (\n STARR<\/jats:styled-content>\n ; 10 additional patients have had a continued response to\n STARR<\/jats:styled-content>\n ). Eleven (23%) had intermittent reducible external prolapse. Epithelial ulcer healing was reported in all patients at 3\u00a0months. The\n ODS<\/jats:styled-content>\n scores improved by 68% (\n P\u00a0<\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.0001) and quality of life (\n Q<\/jats:styled-content>\n o\n L<\/jats:styled-content>\n ; Birmingham Bowel and Urinary Symptoms Questionnaire\u201022) scores improved by 45% (\n P\u00a0<\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.0001). There was a significant improvement in bowel visual analogue scale (\n VAS<\/jats:styled-content>\n ) scores at 3 and 12\u00a0months (\n P\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.0007). Sustained improvement in\n Q<\/jats:styled-content>\n o\n L<\/jats:styled-content>\n and\n VAS<\/jats:styled-content>\n scores was maintained at 2\u00a0years and continued in the 52% followed up for between 3 and 15\u00a0years. There were four (8%) symptomatic\n ODS<\/jats:styled-content>\n recurrences: posterior rectal wall prolapse successfully treated by\n STARR<\/jats:styled-content>\n (3) and one symptom free for 2\u00a0years following a temporary loop ileostomy. There were two recurrences (4%).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n LVMR<\/jats:styled-content>\n appears to provide a sustained improvement in\n Q<\/jats:styled-content>\n o\n L<\/jats:styled-content>\n ,\n VAS<\/jats:styled-content>\n and patient satisfaction in patients with\n SRUS<\/jats:styled-content>\n . Morbidity, recurrence and safety profiles are low.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/codi.12077","type":"journal-article","created":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T15:20:28Z","timestamp":1351524028000},"page":"575-581","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["EXPRESSION OF CONCERN: Laparoscopic ventral mesh rectopexy in the management of solitary rectal ulcer syndrome: a cause for optimism?"],"prefix":"10.1111","volume":"15","author":[{"given":"A. 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