{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T02:38:49Z","timestamp":1785379129917,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,4,25]],"date-time":"2013-04-25T00:00:00Z","timestamp":1366848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Ligation of the intersphincteric fistula tract (<jats:styled-content style=\"fixed-case\">LIFT<\/jats:styled-content>) is a novel sphincter\u2010preserving technique for anal fistula. This pilot study was designed to evaluate the results in patients with a recurrent fistula.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Seventeen patients [nine men; median age 49 (range, 30\u201376) years] with a recurrent trans\u2010sphincteric fistula were treated with a <jats:styled-content style=\"fixed-case\">LIFT<\/jats:styled-content> procedure between <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>une 2008 and <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>ebruary 2011. All were followed prospectively for a median of 16 (range, 5\u201327) weeks with clinical examination. Fifteen followed for 13.5 (range, 8\u201326) months by clinical examination also had three\u2010dimensional (3<jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>) anal ultrasound.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The duration of the procedure was 35 (range, 18\u201370) min. One patient developed a small local haematoma and one had a subcutaneous infection, but otherwise there was no morbidity. At follow up, 11 (65%) patients had a successful closure, two (12%) had a remaining sinus and four (23%) had a persistent fistula. The incidence of persistent or recurrent fistulae at 13.5\u00a0months was six (40%) of 15 patients. No <jats:italic>de novo<\/jats:italic> faecal incontinence was reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">LIFT<\/jats:styled-content> is a safe procedure for patients with recurrent anal fistula, with healing at short\u2010term and medium\u2010term follow\u2010up comparable with or superior to that of other sphincter\u2010preserving techniques. Larger studies with a longer follow up are needed to define the ultimate role of <jats:styled-content style=\"fixed-case\">LIFT<\/jats:styled-content> in patients with recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12104","type":"journal-article","created":{"date-parts":[[2013,1,15]],"date-time":"2013-01-15T17:52:44Z","timestamp":1358272364000},"page":"592-595","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Efficacy of <scp>LIFT<\/scp> for recurrent anal fistula"],"prefix":"10.1111","volume":"15","author":[{"given":"J.\u2010P.","family":"Lehmann","sequence":"first","affiliation":[{"name":"Surgical Department \u00d6stersunds Sjukhus \u00d6stersund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Graf","sequence":"additional","affiliation":[{"name":"Akademiska Sjukhuset Uppsala Institution of Surgical Sciences Uppsala University Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-6612-3"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-6708-9"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-005-0288-1"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e31819c96ac"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-1318.2003.00459.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02235039"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-7248-z"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-7249-y"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800800651"},{"key":"e_1_2_6_12_1","first-page":"581","article-title":"Total anal sphincter saving technique for fistula\u2010in\u2010ano; the ligation of intersphincteric fistula tract","volume":"90","author":"Rojanasakul A","year":"2007","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181c160c4"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181bb869f"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02723.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-011-0779-0"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.12104","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.12104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,20]],"date-time":"2025-04-20T09:03:22Z","timestamp":1745139802000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.12104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,25]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["10.1111\/codi.12104"],"URL":"https:\/\/doi.org\/10.1111\/codi.12104","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,25]]},"assertion":[{"value":"2012-04-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-08-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-04-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}