{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:24:11Z","timestamp":1760984651344},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T00:00:00Z","timestamp":1361923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Slow colonic transit time (<jats:styled-content style=\"fixed-case\">CTT<\/jats:styled-content>) and pelvic floor dyssynergia (<jats:styled-content style=\"fixed-case\">PFD<\/jats:styled-content>) are major contributors to constipation in patients with Parkinson's disease (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>). However, no symptom survey yet exists that effectively differentiates the contributing aetiologies. The significance of individual pelvic floor musculature behaviours and their relationship with colorectal dysmotility in constipated patients with <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> are still controversial and need further clarification. We aimed to investigate how differentiated constipation\u2010related symptoms of <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> patients with constipation may identify constipation groupings and to register the pathophysiological features of the pelvic musculature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Our subjects undertook <jats:styled-content style=\"fixed-case\">CTT<\/jats:styled-content>, defaecography and the <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>nowles\u2013<jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>ccersley\u2013<jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cott Symptom questionnaire. The pathological aetiologies were categorized as group 1 (slow <jats:styled-content style=\"fixed-case\">CTT<\/jats:styled-content>) and\/or group 2 (puborectalis syndrome) and\/or group 3 (pubococcygeus syndrome), in accordance with the <jats:styled-content style=\"fixed-case\">CTT<\/jats:styled-content> and defaecography results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Constipation\u2010related symptoms such as incomplete evacuation and defaecation difficulty yielded high post\u2010test probabilities (81% and 88%, respectively) in groups 3 and 2, but a low post\u2010test probability in group 1 (58%). Changes in the anorectal angle and perineum descent during straining were significantly correlated with <jats:styled-content style=\"fixed-case\">CTT<\/jats:styled-content> (<jats:italic>r\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.57 and <jats:italic>r\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.61, respectively) and with each other (<jats:italic>r\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.82).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings that neural control of the puborectalis and pubococcygeus, along with colorectal peristalsis, were in a similar state of degeneration is key information that should assist physicians to instigate more effective management for colonic dysmotility or <jats:styled-content style=\"fixed-case\">PFD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12105","type":"journal-article","created":{"date-parts":[[2013,1,15]],"date-time":"2013-01-15T17:52:46Z","timestamp":1358272366000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Early recognition of pelvic floor dyssynergia and colorectal assessment in <scp>P<\/scp>arkinson's disease associated with bowel dysfunction"],"prefix":"10.1111","volume":"15","author":[{"given":"C.\u2010P.","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Radiology Taipei Veterans General Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.\u2010H.","family":"Sung","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy and Assistive Technology School of Medicine National Yang\u2010Ming University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.\u2010C.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Taipei Veterans General Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.\u2010Y.","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Taipei Veterans General Hospital Taipei Taiwan"},{"name":"School of Medicine National Yang\u2010Ming University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,2,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000314478"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520310003200"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870120617"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02769.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.74.2.268"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000316613"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20844"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22260"},{"key":"e_1_2_6_10_1","first-page":"1436","article-title":"Study of an integrated non\u2010motor symptoms questionnaire for Parkinson's disease","volume":"123","author":"Yu B","year":"2010","journal-title":"Chin Med J"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22360"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22672"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2008.01162.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1566-0702(01)00295-8"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02234640"},{"key":"e_1_2_6_16_1","first-page":"974","article-title":"What is the role of the pubococcygeal and puborectal muscles in patients with obstructive defecation disorders? 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