{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:15:45Z","timestamp":1761743745249},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,7,30]],"date-time":"2013-07-30T00:00:00Z","timestamp":1375142400000},"content-version":"vor","delay-in-days":29,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Cytoreductive surgery (<jats:styled-content style=\"fixed-case\">CRS<\/jats:styled-content>) combined with hyperthermic intraperitoneal chemotherapy (<jats:styled-content style=\"fixed-case\">HIPEC<\/jats:styled-content>) is a treatment option with curative intent for selected patients with peritoneal carcinomatosis (<jats:styled-content style=\"fixed-case\">PC<\/jats:styled-content>). <jats:styled-content style=\"fixed-case\">CRS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HIPEC<\/jats:styled-content> have been implemented in Denmark at a single centre since 2006. Six years of data on these patients were analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Patients with <jats:styled-content style=\"fixed-case\">PC<\/jats:styled-content> from colorectal or appendiceal cancer, pseudomyxoma peritonei or malignant peritoneal mesothelioma referred to the single national <jats:styled-content style=\"fixed-case\">HIPEC<\/jats:styled-content> centre were prospectively registered from June 2006 to July 2012. Morbidity, 30\u2010day mortality and long\u2010term survival of patients who underwent <jats:styled-content style=\"fixed-case\">CRS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HIPEC<\/jats:styled-content> were analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 80 patients underwent <jats:styled-content style=\"fixed-case\">CRS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HIPEC<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">PC<\/jats:styled-content> originated from colorectal cancer in 34 patients, pseudomyxoma peritonei in 29, appendiceal cancer in 13 and malignant peritoneal mesothelioma in four patients. Thirty\u2010two patients had one or more complications during the hospital stay. The 30\u2010day mortality rate was 1.3%. The predicted 2\u2010, 3\u2010 and 5\u2010year survival was 60%, 47% and 38% in patients with <jats:styled-content style=\"fixed-case\">PC<\/jats:styled-content> from colorectal cancer, and 100%, 93% and 73% in pseudomyxoma peritonei patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">CRS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HIPEC<\/jats:styled-content> is a safe procedure when centralized as in Denmark. Favourable long\u2010term outcome was achieved in selected patients with <jats:styled-content style=\"fixed-case\">PC<\/jats:styled-content> from colorectal cancer and pseudomyxoma peritonei. Short\u2010term and long\u2010term outcomes were comparable to results from international centres.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12185","type":"journal-article","created":{"date-parts":[[2013,3,5]],"date-time":"2013-03-05T02:46:23Z","timestamp":1362451583000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis: the Danish experience"],"prefix":"10.1111","volume":"15","author":[{"given":"L. H.","family":"Iversen","sequence":"first","affiliation":[{"name":"Department of Surgery Aarhus University Hospital THG Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. 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