{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T09:13:33Z","timestamp":1794042813022,"version":"4.8.0"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,6,24]],"date-time":"2013-06-24T00:00:00Z","timestamp":1372032000000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      Laparoscopic ventral mesh rectopexy (\n                      <jats:styled-content style=\"fixed-case\">VMR<\/jats:styled-content>\n                      ) is a surgical option for internal and external rectal prolapse with low perioperative morbidity and low recurrence rates. Use of synthetic mesh in the pelvis may be associated with complications such as fistulation, erosion and dyspareunia. Biological meshes may avoid these complications, but the long\u2010term outcome is uncertain. Debate continues as to which type of mesh is optimal for laparoscopic\n                      <jats:styled-content style=\"fixed-case\">VMR<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      A literature search was performed of electronic databases including\n                      <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>\n                      ,\n                      <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                      mbase and\n                      <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                      copus (2000\u201312). Studies describing outcomes relating to the mesh were included for review. Only English language studies were included.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thirteen observational studies reported the outcome of 866 patients following laparoscopic\n                      <jats:styled-content style=\"fixed-case\">VMR<\/jats:styled-content>\n                      . Eleven reported the outcome using synthetic mesh with a median follow\u2010up ranging from 7 to 74\u00a0months. Two studies reported the outcome with biological mesh with a median follow\u2010up of 12\u00a0months. Pooled analysis of the studies demonstrated that 767 patients had a repair with synthetic mesh and 99 with a biological implant. There was no difference in recurrence (3.7\n                      <jats:italic>vs<\/jats:italic>\n                      4.0%,\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      =\n                      <jats:italic>\u00a0<\/jats:italic>\n                      0.78) or mesh complications (0.7\n                      <jats:italic>vs<\/jats:italic>\n                      0%,\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      =\n                      <jats:italic>\u00a0<\/jats:italic>\n                      1.0%) between synthetic and biological mesh repair.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Biological meshes appear to be as effective as synthetic meshes in the short term for laparoscopic\n                      <jats:styled-content style=\"fixed-case\">VMR<\/jats:styled-content>\n                      . Mesh complication rates are low in both groups. Long\u2010term follow\u2010up is required to ascertain if these findings persist.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.12219","type":"journal-article","created":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T04:38:29Z","timestamp":1363840709000},"page":"650-654","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":108,"title":["Synthetic or biological mesh use in laparoscopic ventral mesh rectopexy \u2013 a systematic review"],"prefix":"10.1111","volume":"15","author":[{"given":"N. J.","family":"Smart","sequence":"first","affiliation":[{"name":"Exeter Surgical Health Services Research Unit (HeSRU) Royal Devon and Exeter NHS Foundation Trust Exeter UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Pathak","sequence":"additional","affiliation":[{"name":"St James's University Hospital Leeds West Yorkshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Boorman","sequence":"additional","affiliation":[{"name":"Exeter Surgical Health Services Research Unit (HeSRU) Royal Devon and Exeter NHS Foundation Trust Exeter UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I. 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