{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:17:24Z","timestamp":1762352244650},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,11,5]],"date-time":"2013-11-05T00:00:00Z","timestamp":1383609600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Sphincter\u2010saving rectal cancer management affects anorectal function. This study evaluated persisting anorectal dysfunction and its impact on patients' well\u2010being.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Seventy\u2010nine patients with a follow\u2010up of 12\u201337 (median 22) months and 79 age\u2010 and sex\u2010matched control subjects completed questionnaires.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median number of diurnal bowel movements was three in patients and one in controls (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.0001). Nocturnal defaecation occurred in 53% of patients. The median Vaizey score was 8 in patients and 4 in controls (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.0001). Urgency without incontinence was reported by 47% of patients and 49% of controls (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.873), soiling by 28% of patients and 3% of controls (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.0001), incontinence for flatus by 73% of patients and 49% of controls (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.0019), and incontinence for solid stools by 16% of patients and 4% of controls (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.0153). Incontinence of liquid stools occurred in 17 of 20 patients and in one of five controls who had liquid stools (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.0123). Incontinence for gas, liquid or solid stool occurred once or more weekly in 47%, 19% and 6% of patients respectively. Evacuation difficulties were reported by 98% of patients, but also by 77% of controls. Neoadjuvant radio(chemo)therapy adversely affected defaecation frequency and continence. Incontinence was associated with severe discomfort in 50% of patients, severe anxiety in 40% and severe embarrassment in 48%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Anorectal dysfunction is a frequent problem after management of rectal cancer with an impact on the well\u2010being of patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12291","type":"journal-article","created":{"date-parts":[[2013,5,21]],"date-time":"2013-05-21T06:58:33Z","timestamp":1369119513000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Persisting anorectal dysfunction after rectal cancer surgery"],"prefix":"10.1111","volume":"15","author":[{"given":"A.","family":"Maris","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Sciences Neuromotor Rehabilitation Research Group KU Leuven Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Penninckx","sequence":"additional","affiliation":[{"name":"Department of Abdominal Surgery University Clinic Gasthuisberg Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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