{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T20:30:53Z","timestamp":1788553853914,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,10,24]],"date-time":"2013-10-24T00:00:00Z","timestamp":1382572800000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Prolonged ileus, low\u2010grade fever and abdominal discomfort are common during the first week after colonic resection. Undiagnosed anastomotic leak carries a poor outcome and computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) scan is the best imaging tool for assessing postoperative abdominal complications. We used a <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> scan\u2010based model to quantify the risk of anastomotic leak after colorectal surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A case\u2013control analysis of 74 patients who underwent clinico\u2010radiological evaluation after colorectal surgery for suspicion of anastomotic leak was undertaken and a multivariable analysis of risk factors for leak was performed. A logistic regression model was used to identify determinant variables and construct a predictive score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 74 patients with a clinical suspicion of anastomotic leak, 17 (23%) had this complication confirmed following repeat laparotomy. In multivariate analysis, three variables were associated with anastomotic leak: (1) white blood cells count &gt;\u00a09\u00a0\u00d7\u00a010<jats:sup>9<\/jats:sup>\/l (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a014.8); (2) presence of \u2265\u00a0500\u00a0cm<jats:sup>3<\/jats:sup> of intra\u2010 abdominal fluid (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a013.4); and (3) pneumoperitoneum at the site of anastomosis (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a09.9). Each of these three parameters contributed one point to the risk score. The observed risk of leak was 0, 6, 31 and 100%, respectively, for patients with scores of 0, 1, 2 and 3. The area under the receiver operating characteristic curve for the score was 0.83 (0.72\u20130.94).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> scan\u2010based model seems clinically promising for objective quantification of the risk of a leak after colorectal surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12305","type":"journal-article","created":{"date-parts":[[2013,5,25]],"date-time":"2013-05-25T15:36:53Z","timestamp":1369496213000},"page":"1295-1300","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["<scp>CT<\/scp> scan\u2010based modelling of anastomotic leak risk after colorectal surgery"],"prefix":"10.1111","volume":"15","author":[{"given":"P.","family":"Gervaz","sequence":"first","affiliation":[{"name":"Department of Surgery Geneva University Hospital and Medical School Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Platon","sequence":"additional","affiliation":[{"name":"Department of Radiology Geneva University Hospital and Medical School Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. C.","family":"Buchs","sequence":"additional","affiliation":[{"name":"Department of Surgery Geneva University Hospital and Medical School Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Rocher","sequence":"additional","affiliation":[{"name":"Department of Radiology Geneva University Hospital and Medical School Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Perneger","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology Geneva University Hospital and Medical School Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.\u2010A.","family":"Poletti","sequence":"additional","affiliation":[{"name":"Department of Radiology Geneva University Hospital and Medical School Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-007-0399-3"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(99)00028-9"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0007-1323.2001.01829.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(99)00207-0"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000225083.27182.85"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2004.12.011"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sult.2004.03.004"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.165.3.7645472"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-009-0925-4"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-008-0487-z"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-004-0652-y"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-007-0354-3"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-006-0708-x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2006.08.004"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002610000036"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-011-1262-0"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2007.01300.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-012-1867-9"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-004-0047-7"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-003-0498-8"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcodi.12305","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.12305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T00:33:25Z","timestamp":1696293205000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.12305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":20,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1111\/codi.12305"],"URL":"https:\/\/doi.org\/10.1111\/codi.12305","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"2012-09-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-01-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}