{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T16:01:48Z","timestamp":1783699308911,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,11,5]],"date-time":"2013-11-05T00:00:00Z","timestamp":1383609600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the contribution of the pudendal nerve to the anal continence mechanism by determining the correlation between pudendal nerve terminal motor latency (<jats:styled-content style=\"fixed-case\">PNTML<\/jats:styled-content>) and resting and squeeze anal canal pressures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>In all, 1051 patients were investigated with anorectal physiology studies between January 1998 and July 2010. Of these, 213 patients had intact anal sphincters on endoanal ultrasound and had undergone <jats:styled-content style=\"fixed-case\">PNTML<\/jats:styled-content> testing and anal manometry with measurement of resting and squeeze pressures. The relationship between <jats:styled-content style=\"fixed-case\">PNTML<\/jats:styled-content> and mean resting and squeeze pressures was compared in these patients with an intact anal sphincter. Values were compared using a two\u2010sample <jats:italic>t<\/jats:italic> test with equal variances. A <jats:italic>P<\/jats:italic> value of &lt;\u00a00.05 was considered significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of these patients 40.8% had normal <jats:styled-content style=\"fixed-case\">PNTML<\/jats:styled-content> bilaterally, 9.9% had slow <jats:styled-content style=\"fixed-case\">PNTML<\/jats:styled-content> bilaterally and 21.6% had a unilateral slow <jats:styled-content style=\"fixed-case\">PNTML<\/jats:styled-content>. Mean resting pressure was significantly reduced in patients with unilateral slow and bilateral slow <jats:styled-content style=\"fixed-case\">PNTML<\/jats:styled-content> compared with normal. The magnitude of the reduction was 28% and 19% respectively. Mean squeeze pressure was significantly reduced in patients with unilateral slow and bilateral slow <jats:styled-content style=\"fixed-case\">PNTML<\/jats:styled-content> compared with normal. The magnitude of the reduction was 18% and 23% respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients with an intact anal sphincter, either unilaterally or bilaterally prolonged <jats:styled-content style=\"fixed-case\">PNTML<\/jats:styled-content>s are associated with significantly decreased resting and squeeze pressures. Our results suggest that both internal and external sphincter function is impaired with pudendal nerve injury. The inhibition of internal sphincter function may be due to damage of autonomic, principally sympathetic fibres carried in the pudendal nerve.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.12368","type":"journal-article","created":{"date-parts":[[2013,7,29]],"date-time":"2013-07-29T18:03:50Z","timestamp":1375121030000},"page":"1410-1415","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Prolonged pudendal nerve terminal motor latency is associated with decreased resting and squeeze pressures in the intact anal sphincter"],"prefix":"10.1111","volume":"15","author":[{"given":"A.","family":"Loganathan","sequence":"first","affiliation":[{"name":"Department of Surgery Flinders Medical Centre Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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